- 询价
- Miltenyi Biotec
- 德国
- 130-133-019
- 2025年12月09日
- Flow cytometry
- human cell line
- human
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- 详细信息
- 文献和实验
- 技术资料
- 免疫原：
VEGFR-1 (Flt-1)
- 亚型：
recombinant human IgG1
- 形态：
Reagents are supplied in buffer containing stabilizer and 0.05% sodium azide.
- 保存条件：
避光，2-8℃
- 克隆性：
REA569
- 标记物：
PE-Vio 615
- 适应物种：
human
- 保质期：
24个月
- 供应商：
Miltenyi Biotec
- 宿主：
human cell line
- 应用范围：
Flow cytometry
- 浓度：
1:50
- 抗体英文名：
VEGFR-1 (Flt-1) Antibody, anti-human, REAfinity™
- 抗体名：
VEGFR-1 (Flt-1) Antibody, anti-human, REAfinity™
- 规格：
100 tests in 200 µL
Identification and enumeration of VEGFR-1 (Flt-1)+ cells by flow cytometryClone REA569 recognizes the human VEGFR-1 antigen, also known as Flt-1, belonging to the class III subfamily of receptor tyrosine kinases. Vascular endothelial growth factors (VEGFs) stimulate cellular responses by binding to tyrosine kinase receptors on the cell surface, causing them to dimerize, and become activated through transphosphorylation. VEGFs are produced by endothelial, hematopoietic, and stromal cells in response to hypoxia and upon stimulation by growth factors such as transforming growth factor beta (TGF-β), interleukins, or platelet-derived growth factors (PDGFs). | Additional information: Clone REA569 displays negligible binding to Fc receptors | | | |
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文献和实验该产品被引用文献
Grunewald, F. S. et al. (2010) Structure-function analysis of VEGF receptor activation and the role of coreceptors in angiogenic signaling. Biochim. Biophys. Acta 1804 (3): 567–580. | Riccioni, R. et al. (2007) Expression of Tie-2 and other receptors for endothelial growth factors in acute myeloid leukemias is associated with monocytic features of leukemic blasts. Stem Cells 25 (8): 1862–1871. | Stuttfeld, E. et al. (2009) Structure and function of VEGF receptors. Int J Biochem Mol Biol 61 (9): 915–922. | Shibuya, M. (2001) Structure and function of VEGF/VEGF-receptor system involved in angiogenesis. Cell Struct. Funct. 26 (1): 25–35.
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VEGFR-1 (Flt-1) Antibody, anti-human, PE-Vio® 615, REAfinity™, 100 tests in 200 µL
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