- 询价
- Miltenyi Biotec
- 德国
- 130-110-547
- 2025年12月09日
- Intracellular flow cytometry
- human cell line
- human
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- 详细信息
- 文献和实验
- 技术资料
- 免疫原：
Under-phospho Rb
- 亚型：
recombinant human IgG1
- 形态：
Reagents are supplied in buffer containing stabilizer and 0.05% sodium azide.
- 保存条件：
避光，2-8℃
- 克隆性：
REA708
- 标记物：
PE
- 适应物种：
human
- 保质期：
24个月
- 供应商：
Miltenyi Biotec
- 宿主：
human cell line
- 应用范围：
Intracellular flow cytometry
- 浓度：
1:50
- 抗体英文名：
Under-phospho Rb Antibody, anti-human, REAfinity™
- 抗体名：
Under-phospho Rb Antibody, anti-human, REAfinity™
- 规格：
100 tests in 200 µL
Identification and enumeration of Under-phospho Rb+ cells by flow cytometryClone REA708 recognizes the human Under-phospho Rb, also known as underphosphorylated Rb protein (retinoblastoma protein). The retinoblastoma protein is a nuclear phosphoprotein which acts as a tumor suppressor in normal cells. The underphosphorylated, active form of the retinoblastoma protein is present in resting or completely differentiated cells and can interact with E2F1 and represses its transcription activity, which leads to cell cycle arrest. The phosphorylated forms of retinoblastoma protein are found in proliferating cells. | Additional information: Clone REA708 displays negligible binding to Fc receptors.
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文献和实验该产品被引用文献
Chellappan, S. et al. (1992) Adenovirus E1A, simian virus 40 tumor antigen, and human papillomavirus E7 protein share the capacity to disrupt the interaction between transcription factor E2F and the retinoblastoma gene product. Proc. Natl. Acad. Sci. U.S.A. 89 (10): 4549–4553. | Harbour, J. W. et al. (2000) Rb function in cell-cycle regulation and apoptosis. Nat. Cell Biol. 2 (4): 65–67. | Ren, S. et al. (2004) Cyclin C/cdk3 promotes Rb-dependent G0 exit. Cell 117 (2): 239–251.
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Under-phospho Rb Antibody, anti-human, PE, REAfinity™, 100 tests in 200 µL
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