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- 详细信息
- 文献和实验
- 技术资料
- 免疫原:
TCR Vβ8.1, 8.2
- 亚型:
recombinant human IgG1
- 形态:
Reagents are supplied in buffer containing stabilizer and 0.05% sodium azide.
- 保存条件:
避光,2-8℃
- 克隆性:
REA585
- 标记物:
FITC
- 适应物种:
mouse
- 保质期:
24个月
- 供应商:
Miltenyi Biotec
- 宿主:
human cell line
- 应用范围:
Flow cytometry, MICS (MACSima Imaging Cyclic Staining), Immunofluorescence, Immunohistochemistry
- 浓度:
1:10
- 抗体英文名:
TCR Vβ8.1, 8.2 Antibody, anti-mouse, REAfinity™
- 抗体名:
TCR Vβ8.1, 8.2 Antibody, anti-mouse, REAfinity™
- 规格:
30 µg in 1 mL
Identification and enumeration of TCR Vβ8.1, 8.2+ cells by flow cytometryClone REA585 recognizes the mouse Vβ8.1, 8.2 T cell receptor (TCR Vβ8.1, 8.2) but not Vβ8.3. Vβ8.1 and 8.2 are variants of the TCR β chain that associates with the TCR α chain. The TCR is responsible for recognizing antigens bound to major histocompatibility complex (MHC) molecules. It is a disulfide-linked membrane-anchored heterodimeric glycoprotein normally consisting of the highly variable α and β chains. TCR Vβ8.1, 8.2 is expressed on approximately 20 % of peripheral T cells in thymus, spleen, and other lymphoid organs in different mice strains, such as Balb/c, AKR, C57BL/6, AKR/B10.A. | Additional information: Clone REA585 displays negligible binding to Fc receptors
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文献和实验该产品被引用文献
Haskins, K. et al. (1984) The antigen-specific, major histocompatibility complex-restricted receptor on T cells. VI. An antibody to a receptor allotype. J. Exp. Med. 160 (2): 452–471. | Kuchroo, V. K. et al. (1994) T cell receptor (TCR) usage determines disease susceptibility in experimental autoimmune encephalomyelitis: studies with TCR V beta 8.2 transgenic mice. J. Exp. Med. 179 (5): 1659–1664. | Mami-Chouaib, F. et al. (2002) Antitumor cytotoxic T-lymphocyte response in human lung carcinoma: identification of a tumor-associated antigen. Immunol. Rev. 188: 114–121.
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文献支持
TCR Vβ8.1, 8.2 Antibody, anti-mouse, FITC, REAfinity™, 30 µg in 1 mL
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