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Nuclear Pore Complex Antibody,

anti-human/mouse, APC, REAfinity™, 100 tests in 200 µL
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  • 询价
  • Miltenyi Biotec已认证
  • 德国
  • 130-133-442
  • 2025年12月09日
  • Flow cytometry
  • human cell line
  • human, mouse
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    • 详细信息
    • 文献和实验
    • 技术资料
    • 免疫原

      Nuclear Pore Complex

    • 亚型

      recombinant human IgG1

    • 形态

      Reagents are supplied in buffer containing stabilizer and 0.05% sodium azide.

    • 保存条件

      避光,2-8℃

    • 克隆性

      REA1353

    • 标记物

      APC

    • 适应物种

      human, mouse

    • 保质期

      24个月

    • 供应商

      Miltenyi Biotec

    • 宿主

      human cell line

    • 应用范围

      Flow cytometry

    • 浓度

      1:50

    • 抗体英文名

      Nuclear Pore Complex Antibody, anti-human/mouse, REAfinity™

    • 抗体名

      Nuclear Pore Complex Antibody, anti-human/mouse, REAfinity™

    • 规格

      100 tests in 200 µL

    Identification and enumeration of Nuclear Pore Complex+ cells by flow cytometryClone REA1353 recognizes the Nuclear Pore Complex Proteins (NPCs). NPCs form channels through the nuclear envelope that allow the passage of macromolecules between the cell nucleus and cytoplasm. The nuclear pore complex is a very complex network with a 110 megadalton (MDa) structure consisting of at least 500 protein subunits and has several functions such as regulating the transport of RNA, proteins and ribosome subunits. The proteins that make up the nuclear pore complex are known as nucleoporins. Several diseases are associated with pathologies of nucleoporins, including diabetes, Parkinson's disease or Alzheimer's disease. Mutations of the genes that encode different nucleoporins can lead to the formation of cancerous tumors. | Additional information: Clone REA1353 displays negligible binding to Fc receptors. |

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    图标文献和实验
    该产品被引用文献
    Beck, M. et al. (2017) The nuclear pore complex: understanding its function through structural insight. Nat. Rev. Mol. Cell Biol. 18 (2): 73–89. | Simon, D. N. et al. (2014) Cancer and the nuclear pore complex Adv. Exp. Med. Biol. 773: 285–307. | Guglielmi, V. et al. (2020) Nuclear pore complexes in development and tissue homeostasis. Development 147 (23): 18344. | Lin, D. H. et al. (2019) The Structure of the Nuclear Pore Complex (An Update). Annu Rev. Biochem. 88: 725–783. | Sheffield, L. G. et al. (2006) Nuclear pore complex proteins in Alzheimer disease. J Neuropathol Exp Neurol. 65 (1): 45–54.
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    Nuclear Pore Complex Antibody, anti-human/mouse, APC, REAfinity™, 100 tests in 200 µL
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