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- 详细信息
- 文献和实验
- 技术资料
- 免疫原:
Yeast nuclear preparations.
- 亚型:
Mouse IgG1
- 形态:
Each vial contains 0.1 mg IgG in 0.1 ml (1 mg/ml) of HEPES (pH7.5), 0.01% BSA, 50% glycerol with 0.065% sodium azide. Antibody was purified by Protein-G affinity chromatography.
- 保存条件:
Store at -20°C.
- 克隆性:
单克隆
- 标记物:
见下方详细说明
- 适应物种:
H, R, M, Other
- 保质期:
1-2年
- 抗原来源:
Yeast nuclear preparations.
- 目录编号:
253196
- 级别:
超纯
- 库存:
大量
- 供应商:
Abbiotec
- 宿主:
Mouse
- 应用范围:
E, IF
- 浓度:
见详细说明信息
- 靶点:
Nuclear Pore Complex
- 抗体英文名:
Nuclear Pore Complex Antibody
- 抗体名:
Nuclear Pore Complex Antibody
- 规格:
0.1 ml
Nuclear Pore Complex Antibody产品详细介绍:
| 产品名称: | Nuclear Pore Complex Antibody |
| 说明书: | 【点击查看详细说明及参考图片】 |
| 货号: | 253196 |
| 规格: | 0.1 ml |
| 产品描述: | The nuclear pore complex (NPC) is a very large structure made up of at least 50 different proteins that span the double membrane of the nuclear envelope functioning as a gateway for macromolecular traffic between the cytoplasm and the nucleus. Discrete nuclear pore complex proteins or nucleoporins such as NUP98, NUP180 and p62 have been implicated in autoimmune disease and cancer. Patients with primary biliary cirrhosis (PBC) frequently produce autoantibodies against p62 and NUP180 while NUP98 translocations have been found in patients with acute myelogenous leukemia (AML). |
| 克隆类型: | Mouse Monoclonal Antibody |
| 亚型: | Mouse IgG1 |
| 免疫原: | Yeast nuclear preparations. |
| 适用物种: | H, R, M, Other |
| 应用范围: | E, IF |
| 应用说明: | E: 1:500-1:1,000; IF: 1:50-1:100 |
| 别名: | Yeast nuclear preparations. |
| 形态: | Each vial contains 0.1 mg IgG in 0.1 ml (1 mg/ml) of HEPES (pH7.5), 0.01% BSA, 50% glycerol with 0.065% sodium azide. Antibody was purified by Protein-G affinity chromatography. |
| 保存条件: | Store at -20°C. Minimize freeze-thaw cycles. Product is guaranteed one year from the date of shipment. |
| 参考文献: |
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文献和实验有核膜孔、细孔( pore)、或环纹( annulus)等各种叫法。是位于真核生物核膜上的许多直径为 70— 150毫微米的圆形的特殊构造。在核孔的正中有一个电子密度的高的颗粒,其周围被电子密度低的薄膜包围着,而在薄膜的周围还有八个电子密度的高的颗粒。在核膜表面上的核孔的密度,以及核孔的内径和外径,可因生物的种类和细胞的时期不同而异。通常核孔的密度与核的活性有关,凡核的合成活动越高,则核孔的密度也越大。最初生物学家将核孔命名为细孔,但实际上它并不是经常单纯开放着的孔
A Functional Proteomic Study of the Trypanosoma brucei Nuclear Pore Complex: An Informatic Strategy
The nuclear pore complex (NPC) is the sole mediator of transport between the nucleus and the cytoplasm. The NPC is composed of about 30 distinct proteins, termed nucleoporins or nups. The yeast (Rout et al., J Cell Biol 148:635–651, 2000
Nuclear Pore Complex Structure and Plasticity Revealed by Electron and Atomic Force Microscopy
To study the ultrastructure of nuclear pore complexes (NPCs), a wide spectrum of different electron microscopy (EM) or atomic force microscopy (AFM) techniques can be employed. The combination of these methods can reveal new insights
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