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- 详细信息
- 文献和实验
- 技术资料
- 免疫原:
MSCA-1
- 亚型:
recombinant human IgG1
- 形态:
Reagents are supplied in buffer containing stabilizer and 0.05% sodium azide.
- 保存条件:
避光,2-8℃
- 克隆性:
REA781
- 标记物:
PE-Vio 770
- 适应物种:
human, non-human primate, other
- 保质期:
24个月
- 供应商:
Miltenyi Biotec
- 宿主:
human cell line
- 应用范围:
Flow cytometry
- 浓度:
1:50
- 抗体英文名:
MSCA-1 Antibody, anti-human, REAfinity™
- 抗体名:
MSCA-1 Antibody, anti-human, REAfinity™
- 规格:
30 tests in 60 µL
Identification and enumeration of MSCA-1+ cells by flow cytometryClone REA781 recognizes the human mesenchymal stromal cell antigen-1 (MSCA-1) antigen, a GPI-anchored protein also known as tissue non-specific alkaline phosphatase (TNAP). MSCA-1 was shown to be restricted to mesenchymal stromal cells (MSCs) in the CD271bright population in bone marrow. These CD271brightCD45dim MSCs have a much higher clonogenic capacity compared to the CD271+CD45+ fraction in bone marrow. Therefore, MSCA-1 is a suitable marker to identify MSCs with a high proliferative potential. | Additional information: Clone REA781 displays negligible binding to Fc receptors.
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文献和实验该产品被引用文献
Battula, V. L. et al. (2007) Human placenta and bone marrow derived MSC cultured in serum-free, b-FGF-containing medium express cell surface frizzled-9 and SSEA-4 and give rise to multilineage differentiation. Differentiation 75: 279–291. | Bühring, H. J. et al. (2007) Novel markers for the prospective isolation of human MSC. Ann. N. Y. Acad. Sci. 1106: 262–271. | Rozemuller, H. et al. (2010) Prospective isolation of mesenchymal stem cells from multiple mammalian species using cross-reacting anti-human monoclonal antibodies. Stem Cells Dev. 19: 1911–1921. | Sobiesiak, M. et al. (2010) The mesenchymal stem cell antigen MSCA-1 is identical to tissue non-specific alkaline phosphatase. Stem Cells Dev. 19: 669–677.
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MSCA-1 Antibody, anti-human, PE-Vio® 770, REAfinity™, 30 tests in 60 µL
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