- 询价
- Miltenyi Biotec
- 德国
- 130-106-141
- 2025年12月09日
- Intracellular flow cytometry, MICS (MACSima Imaging Cyclic Staining), Immunofluorescence, Immunohistochemistry
- human cell line
- human, mouse, rat
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- 详细信息
- 文献和实验
- 技术资料
- 免疫原：
MLC2a
- 亚型：
recombinant human IgG1
- 形态：
Reagents are supplied in buffer containing stabilizer and 0.05% sodium azide.
- 保存条件：
避光，2-8℃
- 克隆性：
REA398
- 标记物：
FITC
- 适应物种：
human, mouse, rat
- 保质期：
24个月
- 供应商：
Miltenyi Biotec
- 宿主：
human cell line
- 应用范围：
Intracellular flow cytometry, MICS (MACSima Imaging Cyclic Staining), Immunofluorescence, Immunohistochemistry
- 浓度：
1:10
- 抗体英文名：
MLC2a Antibody, anti-human/mouse/rat, REAfinity™
- 抗体名：
MLC2a Antibody, anti-human/mouse/rat, REAfinity™
- 规格：
100 tests in 1 mL
Identification and enumeration of MLC2a+ cells by flow cytometryClone REA398 recognizes the human, mouse, and rat atrial isoform of the myosin light chain 2 (MLC2a) antigen. Myosin is a hexamer composed of two myosin heavy chains and four myosin light chains. In the heart two different forms of the myosin light chain are expressed, the atrial form (MLC2a) and the ventricular form (MLC2v). MLC2a is expressed at high levels in atrial cardiomyocytes while MLC2v is essentially restricted to ventricular cardiomyocytes, albeit low levels of both MLC2a and MLC2v persist in the inflow tract, the atrioventricular canal, and the outflow tract of the heart during cardiogenesis. MLC2a expression may as well be suitable to identify mouse and human pluripotent stem cell–derived cardiomyocyte subtypes. | Additional information: Clone REA398 displays negligible binding to Fc receptors.
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文献和实验该产品被引用文献
Nishigaki, R. et al. (2002) An extra human chromosome 21 reduces mlc-2a expression in chimeric mice and Down syndrome. Biochem. Biophys. Res. Commun. 295 (1): 112–118. | Hailstones, D. et al. (1992) Differential regulation of the atrial isoforms of the myosin light chains during striated muscle development. J. Biol. Chem. 267 (32): 23295–23300. | Bizy, A. et al. (2013) Myosin light chain 2-based selection of human iPSC-derived early ventricular cardiac myocytes. Stem Cell Res. 11 (3): 1335–1347.
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MLC2a Antibody, anti-human/mouse/rat, FITC, REAfinity™, 100 tests in 1 mL
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