- 询价
- Miltenyi Biotec
- 德国
- 130-120-774
- 2025年12月09日
- Intracellular flow cytometry, MICS (MACSima Imaging Cyclic Staining), Immunofluorescence, Immunohistochemistry
- human cell line
- human
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- 详细信息
- 文献和实验
- 技术资料
- 免疫原：
Nanog
- 亚型：
recombinant human IgG1
- 形态：
Reagents are supplied in buffer containing stabilizer and 0.05% sodium azide.
- 保存条件：
避光，2-8℃
- 克隆性：
REA314
- 标记物：
APC
- 适应物种：
human
- 保质期：
24个月
- 供应商：
Miltenyi Biotec
- 宿主：
human cell line
- 应用范围：
Intracellular flow cytometry, MICS (MACSima Imaging Cyclic Staining), Immunofluorescence, Immunohistochemistry
- 浓度：
1:50
- 抗体英文名：
Nanog Antibody, anti-human, REAfinity™
- 抗体名：
Nanog Antibody, anti-human, REAfinity™
- 规格：
30 tests in 60 µL
Identification and enumeration of Nanog+ cells by flow cytometryClone REA314 recognizes the human Nanog antigen, a homeobox transcription factor also known as ES cell–associated protein 4. Nanog is thought to be a key factor in maintaining pluripotency. It is expressed in the central portion of the morula, the inner cell mass of the blastocyst, in embryonic stem cells (ESC), and embryonic germ cells (EGC). The expression decreases with ESC differentiation. Nanog is thought to function in concert with other factors such as Oct-4 and SOX2 to establish ESC identity. Inhibition of Nanog expression has led to a reduction in tumorigenicity and such in vitro characteristics of stem cells as anchorage independent growth whereas overexpression may increase tumorigenicity. | Additional information: Clone REA314 displays negligible binding to Fc receptors.
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文献和实验该产品被引用文献
Costa, Y. et al. (2013) NANOG-dependent function of TET1 and TET2 in establishment of pluripotency. Nature 495 (7441): 370–374. | Wang, Z. et al. (2012) Distinct lineage specification roles for NANOG, OCT4, and SOX2 in human embryonic stem cells. Cell Stem Cell 10 (4): 440–454. | Chambers, I. et al. (2003) Functional expression cloning of Nanog, a pluripotency sustaining factor in embryonic stem cells. Cell 113 (5): 643–655.
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Nanog Antibody, anti-human, APC, REAfinity™, 30 tests in 60 µL
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