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- 详细信息
- 技术资料
- 免疫原:
PTK7 (CCK-4)
- 亚型:
mouse IgG2aκ
- 形态:
Reagents are supplied in buffer containing stabilizer and 0.05% sodium azide.
- 保存条件:
避光,2-8℃
- 克隆性:
188B
- 标记物:
APC
- 适应物种:
human
- 保质期:
24个月
- 供应商:
Miltenyi Biotec
- 宿主:
mouse
- 应用范围:
Flow cytometry, MICS (MACSima Imaging Cyclic Staining), Immunofluorescence, Immunohistochemistry
- 浓度:
1:11
- 靶点:
PTK7 (CCK-4)
- 抗体英文名:
PTK7 (CCK-4) Antibody, anti-human
- 抗体名:
PTK7 (CCK-4) Antibody, anti-human
- 规格:
100 tests in 1 mL
Detection of human plasmacytoid dendritic cells, type-2 myeloid dendritic cells, and hematopoietic progenitor cells in blood and bone marrowThe Anti-PTK7 (CCK-4) antibody (clone 188B) recognizes human protein tyrosine kinase-7 (PTK7). PTK7, also known as colon carcinoma kinase-4 (CCK-4), is a receptor protein tyrosine kinase (RPTK)–like molecule that contains a catalytically inactive tyrosine kinase domain. PTK7 was identified to be important for neural development as a regulator of planar cell polarity, being required for convergent extension movement and neural tube closure. Using the Anti-PTK7 (CCK-4) antibody, PTK7 expression was recently analyzed on blood and bone marrow cells. PTK7 was shown to be expressed on plasmacytoid dendritic cells, CD141 (BDCA-3)high type-2 myeloid dendritic cells, and CD34+ hematopoietic progenitor cells (HPCs). PTK7 was detected on early (CD34+ CD133+) and late (CD34+ CD133–) HPCs. In tonsils, PTK7 was also found on some T cells.
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PTK7 (CCK-4) Antibody, anti-human, APC, 100 tests in 1 mL
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