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- 详细信息
- 文献和实验
- 技术资料
- 免疫原:
IL-3
- 亚型:
recombinant human IgG1
- 形态:
Reagents are supplied in buffer containing stabilizer and 0.05% sodium azide.
- 保存条件:
避光,2-8℃
- 克隆性:
REA1032
- 标记物:
PE
- 适应物种:
human
- 保质期:
24个月
- 供应商:
Miltenyi Biotec
- 宿主:
human cell line
- 应用范围:
Intracellular flow cytometry
- 浓度:
1:50
- 抗体英文名:
IL-3 Antibody, anti-human, REAfinity™
- 抗体名:
IL-3 Antibody, anti-human, REAfinity™
- 规格:
100 tests in 200 µL
Identification and enumeration of IL-3+ cells by flow cytometryClone REA1032 recognizes the human interleukin-3 (IL-3) antigen, a secreted molecule which belongs to a discrete family of cytokines that regulates the growth, differentiation, migration, and effector function activities of many hematopoietic cells and immunocytes. IL-3 stimulates the differentiation of multipotent hematopoietic stem cells into myeloid progenitor cells or into lymphoid progenitor cells. In addition, IL-3 stimulates proliferation of all cells in the myeloid lineage (granulocytes, monocytes, and dendritic cells), in conjunction with other cytokines. It is secreted by basophils and activated T cells to support growth and differentiation of T cells from the bone marrow in an immune response. Activated T cells can either induce their own proliferation and differentiation, or that of other T cells. | Additional information: Clone REA1032 displays negligible binding to Fc receptors.
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文献和实验该产品被引用文献
Baxter, E. W. et al. (2012) The inducible tissue-specific expression of the human IL-3/GM-CSF locus is controlled by a complex array of developmentally regulated enhancers. J Immunol 189 (9): 4459–4469. | Yang, Y. C. et al. (1986) Human IL-3 (multi-CSF): identification by expression cloning of a novel hematopoietic growth factor related to murine IL-3. Cell 47 (1): 3–10. | Broughton, S. E. et al. (2012) The GM-CSF/IL-3/IL-5 cytokine receptor family: from ligand recognition to initiation of signaling. Immunol. Rev. 250 (1): 277–302.
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IL-3 Antibody, anti-human, PE, REAfinity™, 100 tests in 200 µL
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