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- 详细信息
- 文献和实验
- 技术资料
- 免疫原:
Frizzled-1
- 亚型:
recombinant human IgG1
- 形态:
Reagents are supplied in buffer containing stabilizer and 0.05% sodium azide.
- 保存条件:
避光,2-8℃
- 克隆性:
REA603
- 标记物:
PE
- 适应物种:
human, mouse
- 保质期:
24个月
- 供应商:
Miltenyi Biotec
- 宿主:
human cell line
- 应用范围:
Flow cytometry
- 浓度:
1:50
- 抗体英文名:
Frizzled-1 Antibody, anti-mouse, REAfinity™
- 抗体名:
Frizzled-1 Antibody, anti-mouse, REAfinity™
- 规格:
150 µg in 1 mL
Identification and enumeration of frizzled-1+ cells by flow cytometryClone REA603 recognizes the mouse frizzled-1 antigen. Frizzled-1 is a member of the frizzled family of proteins which encode seven-transmembrane domain proteins that are receptors for the wingless-type MMTV integration site family of signaling proteins. Frizzled-1 is expressed primarily in the developing lung mesenchyme, in adult heart, placenta, kidney, pancreas, prostate, and ovary. Frizzled-1 interacts with Wnt7b. | Additional information: Clone REA603 displays negligible binding to Fc receptors. |
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文献和实验该产品被引用文献
Sagara, N. et al. (1998) Molecular cloning, differential expression, and chromosomal localization of human frizzled-1, frizzled-2, and frizzled-7. Biochem. Biophys. Res. Commun. 252 (1): 117–122. | Gazit, A. et al. (1999) Human frizzled 1 interacts with transforming Wnts to transduce a TCF dependent transcriptional response. Oncogene 18 (44): 5959–5966. | Wang, Z. et al. (2005) Wnt7b activates canonical signaling in epithelial and vascular smooth muscle cells through interactions with Fzd1, Fzd10, and LRP5. Mol. Cell. Biol. 25 (12): 5022–5030.
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Frizzled-1 Antibody, anti-mouse, PE, REAfinity™, 150 µg in 1 mL
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