- 询价
- Miltenyi Biotec
- 德国
- 130-133-405
- 2025年12月09日
- Flow cytometry
- mouse
- human
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- 详细信息
- 技术资料
- 免疫原：
HLA-E
- 亚型：
mouse IgG1κ
- 形态：
Reagents are supplied in buffer containing stabilizer and 0.05% sodium azide.
- 保存条件：
避光，2-8℃
- 克隆性：
3D12
- 标记物：
Biotin
- 适应物种：
human
- 保质期：
24个月
- 供应商：
Miltenyi Biotec
- 宿主：
mouse
- 应用范围：
Flow cytometry
- 浓度：
1:50
- 靶点：
HLA-E
- 抗体英文名：
HLA-E Antibody, anti-human
- 抗体名：
HLA-E Antibody, anti-human
- 规格：
30 tests in 60 µL
Detection of human HLA-E+ cellsThe 3D12 monoclonal antibody recognizes the human HLA-E protein, a member of the human leukocyte antigen family. HLA-E is a non-classical MHC molecule (MHC-Ib) with limited polymorphisms, which is expressed on the cell surface in a heterodimeric complex with β2-microglobulin. HLA-E is ubiquitously expressed and has a specialized role in NK cell recognition. It binds a restricted set of peptides, e.g., derived from other class I leader sequences. The complex is recognized by NKG2A on NK cells. This recognition protects the HLA-E–expressing cell from NK cell killing. Recently HLA-E recognition by a specialised subset of CD8 T cells has been implicated in pathogen recognition as well as autoimmunity.
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HLA-E Antibody, anti-human, Biotin, 30 tests in 60 µL
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