- 询价
- Miltenyi Biotec
- 德国
- 130-135-495
- 2025年12月09日
- MICS (MACSima Imaging Cyclic Staining), Immunofluorescence, Immunohistochemistry
- human cell line
- human
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- 详细信息
- 技术资料
- 免疫原：
Cleaved PARP1
- 亚型：
recombinant human IgG1
- 形态：
Reagents are supplied in buffer containing stabilizer and 0.05% sodium azide.
- 保存条件：
避光，2-8℃
- 克隆性：
REA1316
- 标记物：
APC
- 适应物种：
human
- 保质期：
24个月
- 供应商：
Miltenyi Biotec
- 宿主：
human cell line
- 应用范围：
MICS (MACSima Imaging Cyclic Staining), Immunofluorescence, Immunohistochemistry
- 浓度：
1:50
- 靶点：
Cleaved PARP1
- 抗体英文名：
Cleaved PARP1 Antibody, anti-human, REAfinity™
- 抗体名：
Cleaved PARP1 Antibody, anti-human, REAfinity™
- 规格：
200 µL
Recombinant antibody for the detection of Cleaved PARP1+ cellsClone REA1316 recognizes the human PARP1 enzyme, Poly (ADP-ribose) polymerase 1, that modifies various nuclear proteins by poly(ADP-ribosyl)ation. PARP1 plays a role in DNA repair in response to environmental stress, genomic stability, and programmed cell death. It catalyzes the transfer of ADP-ribose units from NAD+ to a variety of nuclear proteins including topoisomerases, histones, and PARP itself. PARP1 is involved in differentiation, proliferation and tumor transformation. Furthermore PARP can be cleaved by many ICE-like caspases, it is a cleavage- target of the caspase-3 protease activity associated with apoptosis. Cancer tissues express PARP1 to a high extent, including neuroblastoma, testicular and other germ cell tumors, malignant lymphoma and breast and colon cancer. | Additional information: Clone REA1316 displays negligible binding to Fc receptors. |
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Cleaved PARP1 Antibody, anti-human, APC, REAfinity™, 200 µL
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