- 询价
- Miltenyi Biotec
- 德国
- 130-124-533
- 2025年12月09日
- Intracellular flow cytometry, MICS (MACSima Imaging Cyclic Staining), Immunofluorescence, Immunohistochemistry, Mass cytometry
- human cell line
- human, mouse
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- 详细信息
- 技术资料
- 免疫原：
Bcl-6
- 亚型：
recombinant human IgG1
- 形态：
Antibodies are supplied in phosphate-buffered saline (PBS), pH 7.2. The product contains no preservative and is sterile filtered. Always handle under aseptic conditions.
- 保存条件：
避光，2-8℃
- 克隆性：
REA373
- 标记物：
pure
- 适应物种：
human, mouse
- 保质期：
24个月
- 供应商：
Miltenyi Biotec
- 宿主：
human cell line
- 应用范围：
Intracellular flow cytometry, MICS (MACSima Imaging Cyclic Staining), Immunofluorescence, Immunohistochemistry, Mass cytometry
- 靶点：
Bcl-6
- 抗体英文名：
Bcl-6 Antibody, anti-human/mouse, REAfinity™
- 抗体名：
Bcl-6 Antibody, anti-human/mouse, REAfinity™
- 规格：
100 µg in 100 µL
Identification and enumeration of Bcl-6+ cells by mass cytometryClone REA373 recognizes the human and mouse Bcl-6 antigen, a member of the BTB-zinc finger family of proteins. Bcl-6 is a transcriptional repressor, expressed in germinal center T and B cells and in primary immature dendritic cells. It plays critical functions in various cell types within the adaptive and innate compartments of the immune system. Bcl-6 is highly up-regulated in B cells after T cell–dependent antigenic challenge, and is required for formation of germinal centers within which B cells undergo immunoglobulin affinity maturation. It also plays an important role in macrophages, where it mediates a dampening effect on inflammatory signaling through repression of chemokine expression and NF-κB target genes. | Additional information: Clone REA373 displays negligible binding to Fc receptors.
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Bcl-6 Antibody, anti-human/mouse, pure, REAfinity™, 100 µg in 100 µL
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