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- 详细信息
- 技术资料
- 免疫原:
CD87
- 亚型:
mouse IgG1κ
- 形态:
Reagents are supplied in buffer containing stabilizer and 0.05% sodium azide.
- 保存条件:
避光,2-8℃
- 克隆性:
VIM5
- 标记物:
APC-Vio 770
- 适应物种:
human, non-human primate
- 保质期:
24个月
- 供应商:
Miltenyi Biotec
- 宿主:
mouse
- 应用范围:
Flow cytometry
- 浓度:
1:11
- 靶点:
CD87
- 抗体英文名:
CD87 Antibody, anti-human
- 抗体名:
CD87 Antibody, anti-human
- 规格:
30 tests in 300 µL
Identification and enumeration of CD87+ cells by flow cytometryClone VIM5 recognizes CD87, a 36–38 kDa GPI-anchored cell-surface receptor. CD87, also known uPAR, binds uPA and thus facilitating the catalytic C domain of the uPA to come in close proximity of membrane bound plasminogen. uPA is a serine protease, which converts plasminogen into plasmin which in-turn is involved in digestion of various extracellular matrix proteins. CD87 belongs to the Ly6/neurotoxin receptor family and consists of three disulfide-bonded homologous domains, D1, D2, and D3. Function of uPAR is modulated by two inhibitors, PA1 and PA2. The expression of membrane-bound CD87 is found on granulocytes, monocytes/macrophages, dendritic cells, fibroblasts, endothelial cells, and keratinocytes. Multiple known regulatory functions of CD87 include cell migration, leukocyte adhesion, chemotaxis, signal transduction, and tissue remodeling.
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CD87 Antibody, anti-human, APC-Vio® 770, 30 tests in 300 µL
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