CD87 Antibody, anti-human, APC-Vio® 770, 30 tests in 300 µL

CD87 Antibody, anti-human, APC

-Vio® 770, 30 tests in 300 µL
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  • 询价
  • Miltenyi Biotec已认证
  • 德国
  • 130-099-444
  • 2025年12月09日
  • Flow cytometry
  • mouse
  • human, non-human primate
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  • 企业认证

    • 详细信息
    • 技术资料
    • 免疫原

      CD87

    • 亚型

      mouse IgG1κ

    • 形态

      Reagents are supplied in buffer containing stabilizer and 0.05% sodium azide.

    • 保存条件

      避光,2-8℃

    • 克隆性

      VIM5

    • 标记物

      APC-Vio 770

    • 适应物种

      human, non-human primate

    • 保质期

      24个月

    • 供应商

      Miltenyi Biotec

    • 宿主

      mouse

    • 应用范围

      Flow cytometry

    • 浓度

      1:11

    • 靶点

      CD87

    • 抗体英文名

      CD87 Antibody, anti-human

    • 抗体名

      CD87 Antibody, anti-human

    • 规格

      30 tests in 300 µL

    Identification and enumeration of CD87+ cells by flow cytometryClone VIM5 recognizes CD87, a 36–38 kDa GPI-anchored cell-surface receptor. CD87, also known uPAR, binds uPA and thus facilitating the catalytic C domain of the uPA to come in close proximity of membrane bound plasminogen. uPA is a serine protease, which converts plasminogen into plasmin which in-turn is involved in digestion of various extracellular matrix proteins. CD87 belongs to the Ly6/neurotoxin receptor family and consists of three disulfide-bonded homologous domains, D1, D2, and D3. Function of uPAR is modulated by two inhibitors, PA1 and PA2. The expression of membrane-bound CD87 is found on granulocytes, monocytes/macrophages, dendritic cells, fibroblasts, endothelial cells, and keratinocytes. Multiple known regulatory functions of CD87 include cell migration, leukocyte adhesion, chemotaxis, signal transduction, and tissue remodeling.

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