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- 详细信息
- 文献和实验
- 技术资料
- 免疫原:
CD49b
- 亚型:
recombinant human IgG1
- 形态:
Reagents are supplied in buffer containing stabilizer and 0.05% sodium azide.
- 保存条件:
避光,4-8℃
- 克隆性:
REA188
- 标记物:
FITC
- 适应物种:
human
- 保质期:
24个月
- 供应商:
Miltenyi Biotec
- 宿主:
human cell line
- 应用范围:
Flow cytometry, MICS (MACSima Imaging Cyclic Staining), Immunofluorescence, Immunohistochemistry
- 浓度:
1:50
- 抗体英文名:
CD49b Antibody, anti-human, REAfinity™
- 抗体名:
CD49b Antibody, anti-human, REAfinity™
- 规格:
100 tests in 200 µL
Identification and enumeration of CD49b+ cells by flow cytometryClone REA188 recognizes CD49b, also known as integrin α2 chain. CD49b is single-pass, 150 KDa, type I membrane protein. Together with integrin β1 (CD29), CD49b forms the VLA-2 receptor, which binds ligands such as collagen, fibrinogen, and laminin and thus mediate the attachment of several cell types to extracellular matrix. Expression of CD49b is found on lymphocytes, activated T cells, monocytes, epithelial cells, and platelets. | Additional information: Clone REA188 displays negligible binding to Fc receptors. |
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文献和实验该产品被引用文献
Elices, M. J. and Hemler, M. E. (1989) The human integrin VLA-2 is a collagen receptor on some cells and a collagen/laminin receptor on others. Proc. Natl. Acad. Sci. U.S.A. 86: 9906–9910.
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CD49b Antibody, anti-human, FITC, REAfinity™, 100 tests in 200 µL
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