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- 详细信息
- 技术资料
- 免疫原:
IgE
- 亚型:
mouse IgG1κ
- 形态:
Antibodies are supplied in phosphate-buffered saline (PBS), pH 7.2. The product contains no preservative and is sterile filtered. Always handle under aseptic conditions.
- 保存条件:
避光,2-8℃
- 克隆性:
MB10-26D2
- 标记物:
pure-functional grade
- 适应物种:
human, non-human primate
- 保质期:
24个月
- 供应商:
Miltenyi Biotec
- 宿主:
mouse
- 应用范围:
Functional assay, Functional assay
- 靶点:
IgE
- 抗体英文名:
IgE Antibody, anti-human
- 抗体名:
IgE Antibody, anti-human
- 规格:
500 µg in 0.5 mL
Unconjugated antibody for functional assaysAnti-IgE antibodies react with the IgE isotype of human immunoglobulins. IgE is the shortest-lived immunoglobulin with a half-life of two days in serum. IgE plays an important role in allergy. It is especially associated with type 1 hypersensitivity, where IgE shows high-affinity binding to Fc receptors expressed on the surface of mast cells. Antigen binding to Fc receptor–bound IgE upon re-exposure to specific allergens results in degranulation and the release of a variety of mediators, such as histamine and cytokines. | IgE has two main receptors: the high-affinity receptor FcεRI, which is expressed only on mast cells and basophils, and the low-affinity receptor FcεRII (CD23), which is expressed on B cells. | |
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IgE Antibody, anti-human, pure-functional grade, 500 µg in 0.5 mL
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