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- 详细信息
- 文献和实验
- 技术资料
- 免疫原:
CD183 (CXCR3)
- 亚型:
recombinant human IgG1
- 形态:
Reagents are supplied in buffer containing stabilizer and 0.05% sodium azide.
- 保存条件:
避光,4-8℃
- 克隆性:
REA874
- 标记物:
APC
- 适应物种:
rat
- 保质期:
24个月
- 供应商:
Miltenyi Biotec
- 宿主:
human cell line
- 应用范围:
Flow cytometry
- 浓度:
1:50
- 抗体英文名:
CD183 (CXCR3) Antibody, anti-rat, REAfinity™
- 抗体名:
CD183 (CXCR3) Antibody, anti-rat, REAfinity™
- 规格:
30 µg in 200 µL
Identification and enumeration of CD183 (CXCR3)+ cells by flow cytometryClone REA874 recognizes the rat CD183 antigen, also known as CXCR3. CD183 is a member of the CXC chemokine receptor family and is found on activated T cells, B cells, and NK cells during inflammation. CD183 plays a critical role in T cell migration and is important for activated T lymphoblast recruitment. It mediates the proliferation, survival, and angiogenic activity, and functions as a 7-transmembrane spanning receptor for the CXC chemokines CXCL9, CXCL10, and CXCL11. | Additional information: Clone REA874 displays negligible binding to Fc receptors.
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文献和实验该产品被引用文献
Wang, X. et al. (2000) Identification and molecular characterization of rat CXCR3: receptor expression and interferon-inducible protein-10 binding are increased in focal stroke. Mol. Pharmacol. 57 (6): 1190–1198. | Mohan, K. et al. (2005) CXCR3 is required for migration to dermal inflammation by normal and in vivo activated T cells: differential requirements by CD4 and CD8 memory subsets. Eur. J. Immunol. 35 (6): 1702–1711. | Sporici, R. et al. (2010) CXCR3 blockade inhibits T-cell migration into the CNS during EAE and prevents development of adoptively transferred, but not actively induced, disease. Eur. J. Immunol. 40 (10): 2751–2761.
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CD183 (CXCR3) Antibody, anti-rat, APC, REAfinity™, 30 µg in 200 µL
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