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- 详细信息
- 技术资料
- 免疫原:
FcεRIα
- 亚型:
mouse IgG2bκ
- 形态:
Reagents are supplied in buffer containing stabilizer and 0.05% sodium azide.
- 保存条件:
避光,2-8℃
- 克隆性:
CRA1
- 标记物:
PE-Vio 770
- 适应物种:
human
- 保质期:
24个月
- 供应商:
Miltenyi Biotec
- 宿主:
mouse
- 应用范围:
Flow cytometry, MICS (MACSima Imaging Cyclic Staining), Immunofluorescence, Immunohistochemistry, Functional assay
- 浓度:
1:11
- 靶点:
FcεRIα
- 抗体英文名:
FcεRIα Antibody, anti-human
- 抗体名:
FcεRIα Antibody, anti-human
- 规格:
30 tests in 300 µL
Detection of FcεRIα expression on human cellsClone CRA1 detects the α subunit of the human high-affinity Fc receptor for IgE. The receptor is composed of one α-, one β-, and two disulphide-linked γ-chains, of which the α subunit binds IgE1. FcεRIα is expressed on mast and basophil cells, is upregulated in the presence of IgE, and is found on a subset of blood dendritic cells. CRA1 does not inhibit the binding of IgE it induces mast cell activation followed by a histamine release. The FcεRI complex plays an important role in triggering IgE-mediated allergic reactions.
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FcεRIα Antibody, anti-human, PE-Vio® 770, 30 tests in 300 µL
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