- ￥3770
- biorbyt
- orb1240001
- 英国
- 2025年12月08日
- ELISA, IF, IHC-P, WB
- Human
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- 详细信息
- 文献和实验
- 技术资料
- 抗体名：
CD86 Antibody抗体
- 抗体英文名：
CD86 Antibody
- 靶点：
CD86
- 浓度：
1 mg/mL
- 应用范围：
ELISA, IF, IHC-P, WB
- 适应物种：
Human
- 保质期：
6-12个月
- 抗原来源：
详询
- 目录编号：
orb1240001
- 级别：
科研级
- 库存：
88
- 供应商：
biorbyt
- 标记物：
Unconjugated
- 克隆性：
Polyclonal
- 形态：
Liquid
- 亚型：
IgG
- 免疫原：
CD86 antibody was raised against a peptide corresponding to 17 amino acids near the center of human CD86.The immunogen is located within amino acids 160 - 210 of CD86.
- 规格：
0.02 mg
别名:CD86 Antibody: CD86 molecule, B70, B7-2, B7.2, LAB72, CD28LG2
免疫原：CD86 antibody was raised against a peptide corresponding to 17 amino acids near the center of human CD86.The 免疫原 is located within amino acids 160 - 210 of CD86.
预测反应性:Mouse, Rabbit
分子量:Predicted: 36 kDa Observed: 68 kDa
应用注释：CD86 antibody can be used for Western blot at 1 - 2 μg/mL. Antibody can also be used for Immunohistochemistry at 2 μg/mL. For Immunoflorescence start at 20 μg/mL.Antibody validated: Western Blot in human samples; Immunohistochemistry in human samples and Immunofluorescence in human samples. All other applications and species not yet tested.
防腐剂:CD86 Antibody is supplied in PBS containing 0.02% sodium azide.
纯化:CD86 Antibody is affinity chromatography purified via peptide column.
保存说明:Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
NCBI:NP_787058
UniProt ID:P42082
Note:For research use only.
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文献和实验CD86 分子 CD86 常用单克隆抗体或代号： FUN- 1,BU63,GR65;(B7- 2) 主要表达细胞： Ba,M [B] 分子质量(kDa)和结构： gp80(IgSF) 功 能： CD28、CTLA- 4配体,提供T细胞共刺激信号 CD86 Summary: Costimulates IL-2 production and T cell proliferation
Topical Application of siRNA Targeting Cutaneous Dendritic Cells in Allergic Skin Disease
a crucial role in inducing immunity and tolerance. In our recent work, we have shown a successful treatment using CD86 siRNA targeting cutaneous DCs. A costimulatory molecule, CD86, is induced on DCs in situ after antigen uptake, and CD86
B7 家族 白细胞分化抗原及其功能 B7―1和B7-2 B7―1和B7―2分别称CD80和CD86，属B7家族成员。胞膜外区结构属IgSF成员，各有1个V样区和C2区，两者在氨基酸水平上有25％同源性。CD80胞质区较短，富含精氨酸，有1个RRES序列，为钙调蛋白依赖的磷酸化位点；CD86胞质区含有3个PKC磷酸化位点。 在活化的T细胞、B细胞和单核细胞表达水平明显增加。IL-4和TNF-7分别上调B细胞和单核细胞CD86表达
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