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- 技术资料
- 规格:
100ul
| 产品编号 | bs-19765R-BF405 |
| 英文名称 | RBM17 Rabbit pAb, BF405 conjugated |
| 中文名称 | BF405标记的RNA结合蛋白17抗体 |
| 英文别名 | 45 kDa-splicing factor; RBM 17; Rbm17; RNA binding motif protein 17; RNA binding motif protein17; RNA-binding motif protein 17; SPF 45; SPF45; SPF45_HUMAN; Splicing factor(45 kD); Splicing factor(45kD); Splicing factor 45; Splicing factor 45 kDa; Splicing factor 45kDa. |
| 产品应用 | IF=1:100-500 Not yet tested in other applications. |
| 抗体来源 | Rabbit |
| 免疫原 | KLH conjugated synthetic peptide derived from human RBM17 |
| 亚型 | IgG |
| 纯化方法 | affinity purified by Protein A |
| 克隆类型 | Polyclonal |
| 浓度 | 1mg/ml |
| 储存液 | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| 研究领域 | Epigenetics and Nuclear Signaling > DNA / RNA > RNA Processing > Splicing Neuroscience > Neurology process > Neurodegenerative disease |
| 亚细胞定位 | Nucleus. |
| 相似性 | Contains 1 G-patch domain. _x000D_ Contains 1 RRM (RNA recognition motif) domain. |
| 功能 | Splice factor that binds to the single stranded 3'AG at the exon/intron border and promotes its utilization in the second catalytic step. Involved in the regulation of alternative splicing and the utilization of cryptic splice sites. Promotes the utilization of a cryptic splice site created by the beta-110 mutation in the HBB gene. The resulting frameshift leads to sickle cell anemia. |
| 保存条件 | Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles. |
| 背景资料 | This gene encodes an RNA binding protein. The encoded protein is part of the spliceosome complex and functions in the second catalytic step of mRNA splicing. Alternatively spliced transcript variants have been described. Related pseudogenes exist on chromosomes 9 and 15. [provided by RefSeq, Mar 2009] |
| 应用 | 推荐稀释比例 |
| {IF} | {1:100-500} |
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RBM17 | SPF45 Rabbit pAb, BF405 conj.(bs-19765R-BF405)-100ul
¥2980






