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产品信息以Bioss网站为准
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100ul
| 产品编号 | bsm-54798R-FITC |
| 英文名称 | CD30 Recombinant Rabbit mAb, FITC conjugated |
| 中文名称 | FITC标记的CD30重组兔单抗 |
| 英文别名 | CD 30; CD30 antigen; CD30L receptor; Cytokine receptor CD30; D1S166E; KI 1; Ki 1 antigen; Ki-1 antigen; KI1; Lymphocyte activation antigen CD30; TNFRSF 8; TNFRSF8; TNR8_HUMAN; Tumor Necrosis Factor Receptor Superfamily Member 8; Tumor Necrosis Factor Receptor Superfamily Member 8. |
| 产品应用 | IF=1:50-200 Not yet tested in other applications. |
| 抗体来源 | Rabbit |
| 免疫原 | A synthesized peptide derived from human CD30 |
| 亚型 | IgG |
| 纯化方法 | affinity purified by Protein A |
| 克隆类型 | Recombinant |
| 浓度 | 1mg/ml |
| 储存液 | 0.01M TBS(pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| 研究领域 | Cancer > Tumor biomarkers > Receptors Cancer > Tumor immunology > CD markers Immunology > Cell Type Markers > CD > Non-lineage Immunology > Innate Immunity > Cytokines > TNF Superfamily |
| 亚基 | Interacts with TRAF1, TRAF2, TRAF3 and TRAF5. |
| 亚细胞定位 | Isoform Long: Cell membrane; Single-pass type I membrane protein. Isoform Short: Cytoplasm. |
| 组织特异性 | Detected in thymus and in activated splenocytes. |
| 翻译后修饰 | Phosphorylated on serine and tyrosine residues. |
| 相似性 | Contains 6 TNFR-Cys repeats |
| 功能 | Receptor for TNFSF8/CD30L. May play a role in the regulation of cellular growth and transformation of activated lymphoblasts. Regulates gene expression through activation of NF-kappa-B. |
| 保存条件 | Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. |
| 背景资料 | The protein encoded by this gene is a member of the TNF-receptor superfamily. This receptor is expressed by activated, but not by resting, T and B cells. TRAF2 and TRAF5 can interact with this receptor, and mediate the signal transduction that leads to the activation of NF-kappaB. This receptor is a positive regulator of apoptosis, and also has been shown to limit the proliferative potential of autoreactive CD8 effector T cells and protect the body against autoimmunity. Two alternatively spliced transcript variants of this gene encoding distinct isoforms have been reported. [provided by RefSeq, Jul 2008] |
| 应用 | 推荐稀释比例 |
| {IF} | {1:50-200} |
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CD30 Recombinant Rabbit mAb, FITC conjugated(bsm-54798R-FITC)-100ul
¥3200





