- ￥580 - 1680
- Bioss
- bsm-30277A-FITC
- 2025年12月01日
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- 规格：
100T/25T
| 规格： | 100T | 产品价格： | ￥1680.0 |
|---|---|---|---|
| 规格： | 25T | 产品价格： | ￥580.0 |
| 产品编号 | bsm-30277A-FITC |
| 英文名称 | mouse F4/80 Rat mAb, FITC conjugated |
| 中文名称 | FITC标记的小鼠F4/80单克隆抗体 |
| 英文别名 | ADGRE1(F4/80); Cell surface glycoprotein EMR1; Cell surface glycoprotein F4/80; DD7A5 7; Egf like module containing mucin like hormone receptor like 1; Egf like module containing mucin like hormone receptor like sequence 1; EGF like module receptor 1; EGF TM7; EGF-like module receptor 1; EGF-like module-containing mucin-like hormone receptor-like 1; EGFTM7; EMR 1; EMR-1; EMR1 hormone receptor; EMR1_HUMAN; Gpf480; Ly71; Lymphocyte antigen 71; TM7LN3. |
| 产品应用 | Flow-Cyt=10ul/Test Not yet tested in other applications. |
| 抗体来源 | Rat |
| 亚型 | Rat IgG2b, k |
| 性状 | Liquid |
| 纯化方法 | affinity purified by Protein G |
| 克隆类型 | Monoclonal |
| 理论分子量 | 95 kDa |
| 实际分子量 | 160kDa |
| 储存液 | 0.01M PBS (pH7.4), 0.5% BSA, 0.02% Proclin300. |
| 研究领域 | Immunology > Innate Immunity > Macrophage / Inflamm. Tags & Cell Markers > Cell Type Markers > Other Cell Types |
| 亚基 | Belongs to the G-protein coupled receptor 2 family. LN-TM7 subfamily. Contains 6 EGF-like domains. Contains 1 GPS domain. |
| 亚细胞定位 | Cell membrane. |
| 组织特异性 | Wide expression; increased levels in peripheral blood mononuclear cells. |
| 相似性 | Belongs to the G-protein coupled receptor 2 family. LN-TM7 subfamily.
Contains 6 EGF-like domains. Contains 1 GPS domain. |
| 功能 | Could be involved in cell-cell interactions. |
| 保存条件 | Store at 2-8℃. Protect from light. Avoid freezing. |
| 注意事项 | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
| 背景资料 | The epidermal growth factor (EGF)-TM7 family constitutes a group of class B G-protein coupled receptors, which includes CD97, EMR1 (EGF-like molecule containing mucin-like hormone receptor 1, designated F4/80 in mouse), EMR2, EMR3, FIRE, and ETL (1–3). These family members are characterized by an extended extracellular region with several N-terminal EGF domains, and are predominantly expressed on cells of the immune system (1–3). The EGF-TM7 protein family are encoded by a gene cluster on human chromosome 19p13 (1,3,4). The F4/80 molecule is solely expressed on the surface of macrophages and serves as a marker for mature macrophage tissues, including Kupffer cells in liver, splenic red pulp macrophages, brain microglia, gut lamina propria, and Langerhans cells in the skin (1). F4/80/EMR1 undergoes extensive N-linked glycosylation as well as some O-linked glycosylation (5,6). The function of F4/80/EMR1 is unclear, but it is speculated to be involved in macrophage adhesion events, cell migration, or as a G-protein coupled signaling component of macrophages. |
| 应用 | 推荐稀释比例 |
| {Flow-Cyt} | {10ul/Test} |
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mouse F4/80 Rat mAb, FITC conjugated(bsm-30277A-FITC)-100T/25T
￥580 - 1680
