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- bsm-43190R-AP
- 2025年12月01日
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100ul
| 产品编号 | bsm-43190R-AP |
| 英文名称 | SERPINB3 Recombinant Rabbit mAb, AP conjugated |
| 中文名称 | AP标记的丝氨酸蛋白酶抑制剂B3重组兔单抗 |
| 英文别名 | SPB3_HUMAN; Serpin B3; Protein T4-A; Squamous cell carcinoma antigen 1; SCCA-1; SCCA; SCCA1; SCC; T4-A;SSCA1; HsT1196; SCCA-PD; |
| 产品应用 | WB=1:1000-5000, IHC-F=1:200-800 Not yet tested in other applications. |
| 免疫原 | Recombinant human SERPINB3 protein |
| 亚型 | IgG |
| 纯化方法 | affinity purified by Protein A |
| 克隆类型 | Recombinant |
| 浓度 | 1mg/ml |
| 储存液 | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| 研究领域 | Cancer > Tumor biomarkers > Enzymes Cell Biology > Proteolysis / Ubiquitin > Protease inhibitors > Serine protease inhibitors > SERPINs Immunology > Immune System Diseases > Allergens |
| 亚细胞定位 | Cytoplasm. Seems to also be secreted in plasma by cancerous cells but at a low level. |
| 组织特异性 | Squamous cells. Expressed in some hepatocellular carcinoma (at protein level). |
| 相似性 | Belongs to the serpin family. Ov-serpin subfamily. |
| 功能 | May act as a protease inhibitor to modulate the host immune response against tumor cells. |
| 保存条件 | Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles. |
| 背景资料 | Metastasis of a primary tumor to a distant site is determined through signaling cascades that break down interactions between the cell and extracellular matrix proteins. Among the proteins mediating metastasis are serine prote-ases, such as neutrophil elastase.SCCA is transcribed by two nearly identical genes (SCCA1 and SCCA2), and is mainly produced as SCCA1. The human SCCA1 gene encodes a 390 amino acid protein that was originally isolated from a metastatic cervical squamous cell carcinoma. |
| 应用 | 推荐稀释比例 |
| {WB} | {1:1000-5000} |
| {IHC-F} | {1:200-800} |
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文献和实验Enzyme-labeled primary antibody.�> Substrate Reagent Radiolabeled bait protein.�> Exposure to film [Arrows designate sequence of steps of detection strategy] Biotinylated antibody.�>
of a fusion-tagged bait protein Detection with biotinylated bait protein and enzyme (HRP/AP) labeled with avidin or streptavidin Each method has its own advantages and disadvantages. Several methods are used to generate radioactive isotope labels on bait
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