癌胚抗原单克隆抗体（包被）

英文名称 CEA(C3)
中文名称 癌胚抗原单克隆抗体（包被）
别 名 Carcinoembryonic antigen; Carcinoembryonic antigen related cell adhesion molecule 5; Carcinoembryonic antigen-related cell adhesion molecule 5; CD66e; CD66e; CD66e antigen; CEA; CEA; CEACAM5; CEAM5_HUMAN; DKFZp781M2392; Meconium antigen 100; OTTHUMP00000199032; OTTHUMP00000199033; OTTHUMP00000199034.
癌胚抗原单克隆抗体（包被）
说 明 书 0.1ml 0.2ml
研究领域 肿瘤 细胞类型标志物
抗体来源 Mouse
克隆类型 Monoclonal
克 隆 号 C3
交叉反应 Human,
产品应用 WB=1:100-500 ELISA=1:500-1000 IP=1:20-100 IHC-P=1:100-500 IHC-F=1:100-500 IF=1:100-500 （石蜡切片需做抗原修复）
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 150-200kDa
细胞定位 细胞膜
性 状 Lyophilized or Liquid
浓 度 1mg/1ml
免 疫 原 Human Carcino Embryonic Antigen
亚 型 IgG
纯化方法 affinity purified by Protein A
储 存 液 0.01M PBS, pH 7.4 with 10 mg/ml BSA and 0.1% Sodium azide
保存条件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
癌胚抗原单克隆抗体（包被）
产品介绍 background:
CEA-related cell adhesion molecules (CEACAM) belong to the carcinoembryonic antigen (CEA) family. It consists of seven CEACAM (CEACAM 1, CEACAM 3-CEACAM 8) and 11 pregnancy-specific glyco-protein (PSG 1-PSG 11) members. The CEA family proteins belong to the immunoglobulin (Ig) superfamily and are composed of one Ig variable-like (IgV) and a varying number (0-6) of Ig constant-like (IgC) domains. CEACAM molecules are membrane-bound either via a transmembrane domain or a glycosyl phosphatidyl inositol (GPI) anchor. CEACAM molecules are differentially expressed in epithelial cells or in leucocytes. Over-expression of CEA/ CEACAM 5 in tumors of epithelial origin is the basis of its wide-spread use as a tumor marker. The function of CEACAM family members varies widely: they function as cell adhesion molecules, tumor suppressors, regulators of lymphocyte and dendritic cell activation, receptors of Neisseria species and other bacteria.

Function:
Cell surface glycoprotein that plays a role in cell adhesion and in intracellular signaling. Receptor for E.coli Dr adhesins.

Subunit:
Homodimer. Binding of E.coli Dr adhesins leads to dissociation of the homodimer.

Subcellular Location:
Cell membrane; Lipid-anchor, GPI-anchor

Tissue Specificity:
Found in adenocarcinomas of endodermally derived digestive system epithelium and fetal colon.

Post-translational modifications:
Complex immunoreactive glycoprotein with a MW of 180 kDa comprising 60% carbohydrate.

Similarity:
Belongs to the immunoglobulin superfamily. CEA family.
Contains 7 Ig-like (immunoglobulin-like) domains.
癌胚抗原单克隆抗体（包被）
zk-9028R AKAP2蛋白激酶A2抗体
zk-2133R AT2R2血管紧张素Ⅱ受体2抗体
zk-9671R ASH1LASH1蛋白抗体
zk-11385R AADACL2芳香乙酰胺脱乙酰基酶样蛋白2抗体
zk-11388R AAMP血管内皮细胞迁移蛋白抗体
zk-6274R AKR1B10醛糖还原酶相关蛋白质抗体
zk-6275R AKR1C2胆汁酸结合蛋白DDH2抗体
zk-5918R ANGPTL3血管生成素样蛋白3抗体
zk-6276R Acylglycerol Kinase甘油酯激酶线粒体抗体
zk-6189R phospho-alpha Adducin(Ser726)磷酸化内收蛋白a1抗体
zk-4232R ATG16L2自噬体ATG16L2蛋白抗体
zk-6289R ACPT睾丸酸性磷酸酶抗体
zk-6291R Acid Phosphatase酸性磷酸酶抗体
zk-4287R AKIP极光激酶A相互作用蛋白1抗体
zk-7095R APOL6载脂蛋白样蛋白6抗体
zk-7096R ARTS凋亡相关蛋白TGFb信号抗体
zk-11381R A2LD1A2LD1蛋白抗体
zk-11382R A4GNTα1,4-N-乙酰葡糖胺转移酶α4Gn-T抗体
zk-11384R AADAC芳香乙酰胺脱乙酰基酶抗体
zk-11387R AADACL4芳香乙酰胺脱乙酰基酶样蛋白4抗体
zk-11390R AASDHPPT氨基乙二酸半醛脱氢酶磷酸泛酰巯基乙胺转移酶抗体
zk-11391R AASS赖氨酸酮戊二酸还原酶抗体
zk-8728R ANKRD6锚蛋白重复域6抗体
zk-11397R Arginase II精氨酸酶2抗体
zk-11401R AKR1C3醛固酮还原酶家族1成员C3抗体
zk-11408R ACTHR促肾上腺皮质激素受体
zk-11415R AGRP褐黑素相关蛋白ART抗体
zk-11426R Adrenodoxin肾上腺皮质线粒体铁氧还蛋白抗体
zk-11807R AdracalinAllgrove综合征相关蛋白抗体
zk-10180R AAV5 capsid protein VP1腺相关病毒5 VP1抗体
zk-11797R ALDH3A2脂肪醛脱氢酶抗体
zk-11598R AVPR1A抗利尿激素1A抗体