血小板源性生长因子受体-B抗体

血小板源性生长因子受体-B抗体产品标准

浓缩液(1mg/1ml) 亲和纯化抗体

产品应用

WB=1:100-500 Elisa =1:200-1000 IP=1:20-100 IHC=1:100-500 （石蜡切片需做抗原修复）

血小板源性生长因子受体-B抗体产品介绍

细胞膜受体（Membrane Receptors)

The PDGF Receptor Type A (Alpha platelet-derived growth factor receptor precursor, CD140a antigen), a 170kD protein, binds all three isoforms of PDGF with high affinity whereas the PDGF Receptor Type B, a 190kD protein, appears to bind only the PDGF BB homodimer with high affinity. Both receptors are transmembranous, ligand activated protein tyrosine kinases, which phosphorylate a number of important signal transduction proteins, which are bound with differential affinities via SH2 domains. The response of any given cell to PDGF will depend on the types of receptors displayed on the surface and isoforms of PDGF present in the extracellular environment
mol wt:190kDa
Other Aliases:
PDGF BETA-RECEPTOR, PDGF RECEPTOR BETA, PDGF-R-BETA, PDGFR, PDGFR1, PDGFRB ; PDGFRB; CD140B; JTK12; AI528809; PDGFR;PDGFRβ:PDGF Rβ: PDGF Receptor beta; beta-type platelet-derived growth factor receptor precursor

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血小板源性生长因子受体-B抗体