一种肿瘤抑制基因（N端）

一种肿瘤抑制基因（N端）产品标准

浓缩液(1mg/1ml) 亲和纯化抗体

产品应用

WB=1:100-500 Elisa =1:200-1000 IP=1:20-100 IHC=1:100-500 （石蜡切片需做抗原修复）

一种肿瘤抑制基因（N端）产品介绍

PTEN是一种肿瘤抑制基因（N端抗体），在维持细胞的增殖、分化和凋亡平衡起重要作用，该基因在许多肿瘤常表现为突变或杂合性丢失，NMAC1主要用于胶质瘤、乳腺、前列腺癌、非何杰金氏淋巴瘤各种恶性肿瘤的研究.分子量：44KDa
Potential tumor suppressor. Acts as a phosphoinositide3-phosphatase by regulating PtdIns (3,4,5)P3 levels. Involved in regulation of the AKT1 signaling pathway. The unphosphorylated form cooperates with AIP1 to suppress AKT1 activation.The PTEN/MMAC1 discovers the first to have the suppress of the phosphoric acid enzyme activity cancer gene currently.The gene of PTEN locates the chromosome10q23 area, sending forth sex tumor and a few households cancers with the variety to suffer from the comprehensive disease easilyrelevant.The activity that passes to repress the Akt regulates the cell period, the cell ground rule decease and glues to connect.This text discussed PTEN structure, function and its correlationses, the PTEN is in tumor repress function mechanism
Also known as:
• Bannayan Zonana syndrome • BZS a • ITGA 2 • MGC11227 • MHAM • MMAC 1 • MMAC1 • Multiple hamartoma (Cowden syndrome) • Mutated in Mutiple Advanced Cancers 1 • Phosphatase and Tensin Homolog • Phosphatidylinositol 345 trisphosphate 3 phosphatase and dual specificity protein phosphatase PTEN • Phosphatidylinositol 345 trisphosphate 3 phosphatase • Platelet antigen BR • PTEN 1 • PTEN1 • Tensin homolog • TEP 1 • TEP1 • VLA 2 Receptor Alpha Subunitzk-0294zk Goat IgG羊IgG
zk-0360G-HRzk Goat Anti-human IgA/HRP辣根过氧化物酶标记羊抗人IgA
zk-0294zk-Azkzk Goat IgG/APC荧光素APC标记羊IgG(细胞流式同型对照)
zkR-0945zk HSA(Human sermu albumin)/RBITC罗丹明标记人血白蛋白
zk-0345zk human IgM(免疫亲和纯化)人IgM
zk-0302R Rabbit Anti-HRP兔抗HRP
zk-0297zk human IgG(亲和纯化) 人IgG
zk-0360zk human sIgA(亲和纯化) 人分泌型IgA
zk-0297zk-Bio human IgG/Biotin生物素化人IgG
zk-0789zk-zky3 Insulin Protein/Cy3荧光素Cy3标记猪胰岛素蛋白
zk-0296zk Mouse IgG(免疫亲和纯化) 小鼠IgG
zk-0368zk Mouse IgM小鼠IgM (免疫亲和纯化)
zk-0336zk Monkey IgM(亲和纯化) 猴IgM
zk-0296zk-A350 Mouse IgG/Alexa Fluor 350Alexa Fluor 350标记小鼠IgG(细胞流式同型对照)
zk-0296zk-A555 Mouse IgG/Alexa Fluor 555Alexa Fluor 555标记小鼠IgG(细胞流式同型对照)
zk-0774Rs Rabbit anti-Mouse IgA whole serum兔抗小鼠IgA抗血清
zk-0296zk-A647 Mouse IgG/Alexa Fluor 647Alexa Fluor 647标记小鼠IgG(细胞流式同型对照)
zk-0296zk-zky5.5 Mouse IgG/Cy5.5荧光素Cy5.5标记小鼠IgG(细胞流式同型对照)
zk-0283zk-zkE OVA/PE荧光素PE标记鸡卵白蛋白
zkF-0362zk Protein A/FITCFITC标记重组金 黄 色 葡 萄 球 菌蛋白A
zke-0361zk rec Protein G/HRP辣根过氧化物酶标记的重组蛋白G
zkGA-0366R Rabbit Anti-FITC/Gold金标记兔抗荧光素 (10nm/15nm)
zk-0295zk-A488 Rabbit IgG/Alexa Fluor 488Alexa Fluor 488标记兔IgG(细胞流式同型对照)
zk-0295zk-zkE-zky5 Rabbit IgG/PE-Cy5荧光素PE-Cy5标记兔IgG(细胞流式同型对照)
一种肿瘤抑制基因（N端）