淋巴增强因子-1抗体

淋巴增强因子-1抗体产品标准

浓缩液(1mg/1ml) 亲和纯化抗体

产品应用

WB=1:100-500 Elisa =1:200-1000 IP=1:20-100 IHC=1:100-500 （石蜡切片需做抗原修复）

淋巴增强因子-1抗体产品介绍

lef-1是淋巴增强因子/T-细胞因子(LEF/TCF)家族的成员之一,属于高迁移率组分蛋白家族。lef-1也是一个重要的转录因子，是Wnt信号通路的核心成分。
Lymphoid enhancer factor, LEF1, is a transcription factor of the High Mobility Group of DNA binding proteins. It is one member of a family of four proteins referred to as LEF/TCF transcription factors (LEF1, TCF1, TCF3 and TCF4). These factors play crucial roles in WNT/Wingless signaling, a signal transduction cascade that directs cell differentiation. Aberrant activation of the WNT/Wingless pathway is also a root cause in the genesis of certain cancers such as colon cancer, melanoma and breast cancer.
LEF1 is expressed during development in many different differentiating tissues, and in a few tissues after birth. LEF1 expression is required for proper development of breast, teeth, hair, whiskers and the trigeminal nerve. It is redundant with TCF1 (for T cell Factor 1) for correct development of T lymphocytes in the thymus. LEF1 is a 399 amino acid protein. Alternative splice forms of LEF1 and other LEF/TCF family members have been identified, but the expression pattern and relative abundance of these alternative forms have not been well studied. They can appear on immunoblots as small immunoreactive forms.zk-8320R HEATR3HEATR3蛋白抗体
zk-8321R HEATR6乳腺癌增强蛋白抗体
zk-8188R Histone H3 (mono methyl K79)单甲基组蛋白H3K9抗体
zk-8319R HDHD2BHDHD2B蛋白抗体
zk-7626R HAX1造血干细胞特异性相关结合蛋白1抗体
zk-15408R H-2DdI类组织相容性H-2抗原D-Dalpha链抗体
zk-15440R HEATR5AHEAT重复内含蛋白5A蛋白抗体
zk-0244R HSP70热休克蛋白70抗体
zk-11407R HSD17B8羟类固醇脱氢酶17β抗体（17β-HSD8）
zk-15402R HABP4透明质酸结合蛋白4抗体
zk-2285R H5N1 HemagglutininA型流感病毒H5N1凝集素抗体
zk-4619R H1N1++H3N2 nucleocapsid proteinA型流感病毒核衣壳蛋白抗体
zk-4620R H1N1+H5N1+H3N2 nucleocapsid proteinA型流感病毒核衣壳蛋白抗体
zk-4621R H1N1+H5N1+H3N2 nucleocapsid proteinA型流感病毒核衣壳蛋白抗体
zk-15403R Haemophilus influenza BB型流感病毒蛋白抗体
zk-4623R HPV16-E7人类乳头状瘤病毒16-E7抗体
zk-6281R Hepsin跨膜蛋白酶丝氨酸1抗体
zk-6297R HLC3肺癌癌基因蛋白3抗体
zk-4589R High density lipoprotein高密度脂蛋白抗体
zk-6265R HEF1蛋白激酶底物相关蛋白抗体
zk-4942R HIV1 p55+p24+p17艾滋病病毒抗体
zk-2137R H3N2 hemagglutinin流感病毒H3N2血凝素抗体
zk-8547R HPV16 L2人乳头瘤病毒16型L2抗体
zk-10299R H7N9 Matrix Protein 1A型禽流感病毒H7N9 M1蛋白抗体
zk-9508R Hirudin水蛭素抗体
zk-4068R HuC副肿瘤综合症小脑变性相关蛋白抗体
淋巴增强因子-1抗体