- 询价
- R&D
- ZK-0102219
- 美国/中国
- 2025年11月20日
- 科研使用
- Goat，Rabbit，Mouse
- 人，大鼠，小鼠，兔
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- 详细信息
- 文献和实验
- 技术资料
- 靶点：
来电咨询
- 克隆性：
多克隆
- 标记物：
见 说 明 书
- 宿主：
Goat，Rabbit，Mouse
- 适应物种：
人，大鼠，小鼠，兔
- 形态：
液态/粉状
- 应用范围：
科研使用
- 浓度：
1mg/1ml
- 保存条件：
-20℃保存
- Involucrin Polyclonal Antibody保存于运输说明：
- Store at -20°C
- 详细信息：
-
Description Polyclonal Antibody against Involucrin Intended Use **Research Use Only (RUO)**
This product is sold for laboratory research use only, not for human or in-vivo use.Form Antiserum Host Rabbit Species Reactivity Mouse Specificity Involucrin Polyclonal Antibody Involucrin serves as a marker for terminal differentiation of stratified squamous epithelia. The involucrin genes have diverged considerably through evolution and as a consequence antibodies specific for the human molecule do not detect the homologous mouse gene product. This polyclonal antibody was generated against an 18 amino acid peptide (ELHLGKQQESHEPDMAED) predicted from the mouse involucrin gene sequence. Uses This antibody is effective in immunoblotting and immunofluorescence (IF). Suggested Working Dilution The optimal working dilution should be determined for each specific assay condition. - Western blot: 1:1,000*
- IF: 1:1,000
Notes *Predicted MW = 56 kDa, however bands ranging from 56-155 kD are detectable depending on nature of source material (refer to Li ER et al paper below). Storage Store at -20°C. Upon initial thawing, apportion into working aliquots and store at -20°C. Avoid repeated freeze-thaw cycles to prevent denaturing the antibody. For long-term storage, keep the antibody at -80°C. References Involucrin Polyclonal Antibody Merritt AJ, Berika MY, Zhai W, Kirk SE, Ji B, Hardman MJ, Garrod DR. Suprabasal Desmoglein 3 expression in the epidermis of transgenic mice results in hyperproliferation and abnormal differentiation. Mol Cell Biol 22:5846 - 5858, 2002.
Lin AW, Lowe SW. Oncogenic ras activates the ARF-p53 pathway to suppress epithelial cell transformation. PNAS 98:5025-5030, 2001.
Djian P, Easley K, Green H. Targeted ablation of the murine involucrin gene. J Cell Biol 151(2):F5-8, 2000. [IF]
Li ER, Owens DW, Djian P, Watt FM. Expression of involucrin in normal, hyperproliferative and neoplastic mouse keratinocytes. Exp Dermatol 9(6):431-438, 2000. [Wb]
Djian P, Phillips M, Easley K, Huang E, Simon M, Rice RH, Green H. The involucrin genes of the mouse and the rat: study of their shared repeats. Mol Biol Evol 10:1136-1149, 1993.Warranty/Conditions Covance products may not be resold or modified for resale without prior written approval. - Involucrin Polyclonal Antibody
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zk-0294M-zky5 Mouse Anti-Goat IgG/Cy5Cy5标记的小鼠抗羊IgG
zk-0294M-zky5.5 Mouse Anti-Goat IgG/Cy5.5Cy5.5标记的小鼠抗羊IgG
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zk-0295M-zky7 Mouse Anti-rabbit IgG/Cy7Cy7标记的小鼠抗兔IgG
zk-0295M-zkE Mouse Anti-rabbit IgG/PEPE标记的小鼠抗兔IgG
zk-0295M-zkE-zky3 Mouse Anti-rabbit IgG/PE-Cy3PE-Cy3标记的小鼠抗兔IgG
zk-0295M-Azkzk Mouse Anti-rabbit IgG/APCAPC标记的小鼠抗兔IgG
zk-0295M-zky5 Mouse Anti-rabbit IgG/Cy5Cy5标记的小鼠抗兔IgG
zk-0295M-zkE-zky5.5 Mouse Anti-rabbit IgG/PE-Cy5.5PE-Cy5.5标记的小鼠抗兔IgG
zk-0295M-Azk Mouse Anti-rabbit IgG/AP碱性磷酸酶（AP）标记的小鼠抗兔IgG
zk-0295M-RBITzk Mouse Anti-rabbit IgG/RBITC罗丹明标记的小鼠抗兔IgG
zk-0295M-FITzk Mouse Anti-rabbit IgG/FITCFITC标记的小鼠抗兔IgG
zk-0295M-Golzk Mouse Anti-rabbit IgG/Gold胶体金标记的小鼠抗兔IgG
zk-0369M-FITzk Mouse Anti-Rabbit IgM/FITCFITC标记的小鼠抗兔IgM
zk-0369M-Azk Mouse Anti-Rabbit IgM/AP碱性磷酸酶（AP）标记的小鼠抗兔IgM
zk-0369M-Golzk Mouse Anti-Rabbit IgM/Gold胶体金标记的小鼠抗兔IgM
zk-0369M-Bio Mouse Anti-Rabbit IgM/Bio生物素标记的小鼠抗兔IgM
zk-0369M-zky3 Mouse Anti-Rabbit IgM/Cy3Cy3标记的小鼠抗兔IgM
zk-0369M-zky5 Mouse Anti-Rabbit IgM/Cy5Cy5标记的小鼠抗兔IgM
zk-0369M-zky5.5 Mouse Anti-Rabbit IgM/Cy5.5Cy5.5标记的小鼠抗兔IgM
zk-0369M-zky7 Mouse Anti-Rabbit IgM/Cy7Cy7标记的小鼠抗兔IgM
zk-0369M-zkE Mouse Anti-Rabbit IgM/PEPE标记的小鼠抗兔IgM
zk-0369M-Azkzk Mouse Anti-Rabbit IgM/APCAPC标记的小鼠抗兔IgM
zk-0369M-AF350 Mouse Anti-Rabbit IgM/Alexa Fluor 350Alexa Fluor 350标记的小鼠抗兔IgM
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Involucrin Polyclonal Antibody
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