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Nonmuscle Myosin Heavy Chain I

I-B Polyclonal Antibody, Purified
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  • 询价
  • R&D
  • ZK-0100595
  • 美国/中国
  • 2025年11月20日
  • 科研使用
  • Goat,Rabbit,Mouse
  • 人,大鼠,小鼠,兔
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  • 企业认证

    • 详细信息
    • 文献和实验
    • 技术资料
    • 靶点

      来电咨询

    • 克隆性

      多克隆

    • 标记物

      见 说 明 书

    • 宿主

      Goat,Rabbit,Mouse

    • 适应物种

      人,大鼠,小鼠,兔

    • 形态

      液态/粉状

    • 应用范围

      科研使用

    • 浓度

      1mg/1ml

    • 保存条件

      -20℃保存

    • Nonmuscle Myosin Heavy Chain II-B Polyclonal Antibody, Purified详细信息:
    • Description Polyclonal Antibody against Nonmuscle Myosin II Heavy Chain Isoform B
      Intended Use **Research Use Only (RUO)**

      This product is sold for laboratory research use only, not for human or in-vivo use.
      Form Affinity Purified Antibody (Stored in TBS + 0.03% Thimerosal)
      Host Rabbit
      Species Reactivity Human, Rodent
      [Ab] Nonmuscle Myosin Heavy Chain II-B Polyclonal Antibody, Purified 1 mg/mL
      Specificity This antibody was raised against the peptide SDVNETQPPQSE corresponding to the C-terminus of nonmuscle myosin heavy chain isoform B (MHC-B).
      Uses This antibody is effective in immunoblotting (WB) and immunofluorescence (IF).
      Suggested Working Dilution The optimal working dilution should be determined for each specific assay condition.
      • WB: 1:1,000*
      • IF: 1:500
      Notes *Predicted MW = 200 kDa
      Storage Store at -20°C. Upon initial thawing, apportion into working aliquots and store at -20°C. Avoid repeated freeze-thaw cycles to prevent denaturing the antibody. For long-term storage, keep the antibody at -80°C.
      References Ma X, Bao J, Adelstein RS. Loss of cell adhesion causes hydrocephalus in nonmuscle myosin II-B-ablated and mutated mice. Mol Biol Cell 18(6):2305-12, 2007. [IF]

      Golomb E, Ma X, Jana SS, Preston YA, Kawamoto S, Shoham NG, Goldin E, Conti MA, Sellers JR, Adelstein RS. Identification and characterization of nonmuscle myosin II-C, a new member of the myosin II family. J Biol Chem 279(4):2800-8, 2004. [WB, IF]

      Nonmuscle Myosin Heavy Chain II-B Polyclonal Antibody, Purified Song J, Goetz BD, Baas PW, Duncan ID. Cytoskeletal reorganization during the formation of oligodendrocyte processes and branches. Mol Cell Neurosci 17(4):624-636, 2001.

      Kelley CA, Sellers JR, Gard DL, Bui D, Adelstein RS, Baines IC. Xenopus nonmuscle myosin heavy chain isoforms have different subcellular localizations and enzymatic activities. J Cell Biol 134:675-687, 1996.

      Kelley CA, Oberman F, Yisraeli JK, Adelstein RS. A Xenopus nonmuscle myosin heavy chain is phosphorylated by cyclin-p34cdc 2 kinase during meiosis. J Biol Chem 270:1395-1401, 1995.

      Phillips CL, Yamakawa K, Adelstein RS. Cloning of the cDNA encoding human nonmuscle myosin heavy chain-B and analysis of human tissues with isoform-specific antibodies. J Muscl Res Cell Motil 16:379-389, 1995.
      Warranty/Conditions Covance products may not be resold or modified for resale without prior written approval.
    • Nonmuscle Myosin Heavy Chain II-B Polyclonal Antibody, Purified
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