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- 详细信息
- 文献和实验
- 技术资料
- 库存：
60
- 英文名：
Interleukin-16 Human Recombinant, His Tag
- 保质期：
12个月
- 供应商：
上海再康生物科技有限公司
- 保存条件：
见 说 明 书
- 规格：
5µg 20µg 1mg
- IL 16 Human, His
- Interleukin-16 Human Recombinant, His Tag
CATALOGUE NUMBER
CYT-1562
SYNONYMS
IL16, Interleukin-16, LCF, Lymphocyte Chemoattractant Factor, prIL-16, IL-16, FLJ16806, FLJ42735, FLJ44234, HsT19289.INTRODUCTION
IL-16 is a pleiotropic cytokine that functions as a chemoattractant, a modulator of T cell activation, and an inhibitor of HIV replication. The signaling process of IL-16 is mediated by CD4. The product of this gene undergoes proteolytic processing, which is found to yield two functional proteins. IL-16 functions exclusively attributed to the secreted C-terminal peptide, while the N-terminal product may play a role in cell cycle control. Caspase 3 is reported to be involved in the proteolytic processing of this protein. Two transcript variants encoding different isoforms have been found for this gene.IL-16 stimulates a migratory response in cd4+ lymphocytes, monocytes, and eosinophils. Also induces t-lymphocyte expression of interleukin 2 receptor, ligand for cd4.
DESCRIPTION
Interleukin-16 Human Recombinant produced in E.Coli is a single, non-glycosylated polypeptide chain (502-631 a.a) containing 150 amino acids and having a molecular mass of 15.5kDa. The IL-16 is fused to a 20 a.a His-Tag at N-Terminus.
The IL-16 is purified by proprietary chromatographic techniques.
SOURCE
Escherichia Coli.PHYSICAL APPEARANCE
Sterile Filtered solution.FORMULATION
IL-16 His tag protein (1mg/ml) contains 20mM Tris-HCl pH-8, 1mM PMSF & 10% glycerol.STABILITY
Store at 4°C if entire vial will be used within 2-4 weeks.Store, frozen at -20°C for longer periods of time.
Please avoid freeze thaw cycles.
PURITY
Greater than 95.0% as determined by SDS-PAGE.AMINO ACID SEQUENCE
MGSSHHHHHH SSGLVPRGSH MPDLNSSTDS AASASAASDV SVESTAEATV CTVTLEKMSAGLGFSLEGGK GSLHGDKPLT INRIFKGAAS EQSETVQPGD EILQLGGTAM QGLTRFEAWN IIKALPDGPV TIVIRRKSLQ SKETTAAGDS.USAGE
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文献和实验白细胞介素 IL-16 IL-16主要产生细胞：括化T细胞、嗜酸粒细胞 IL16氨基酸数目：130(四聚体) IL16分子质量(kDa)：14～17／56 IL16受体：CD4 IL16主要生物学活性：趋化和活化CD4T细胞、单核细胞和嗜酸粒细胞；诱导嗜酸粒细胞黏附
上海西唐生物科技有限公司 021-55229872, 65333639 www.westang.com 人白介素-16 (IL-16)ELISA 试剂盒 ( 用于血清、血浆、细胞培养上清液和其它生物体液内 ) 原理 本实验采用双抗体夹心 ABC-ELISA 法。用抗人 IL-16 单抗包被于酶标板上，标准品和样品中的 IL-16与单抗结合，加入生物素化的抗人 IL
Immortalization of Human Prostate Cells With the Human Papillomavirus Type 16 E6 Gene
. With the addition of DU145 the list of human experimental prostate cell systems is almost exhausted, although recently new sets of cell lines, immortalized by viral and nonviral genes, have begun to appear to augment the list (1 –5 ).
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