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- 详细信息
- 技术资料
- 供应商:
上海再康生物科技有限公司
- 库存:
大量
- 靶点:
见官方网站
- 级别:
高
- 目录编号:
ESD-300
- 克隆性:
多克隆
- 抗原来源:
见 说 明 书
- 保质期:
6个月
- 抗体英文名:
TRPV1 Channel Deluxe Research Pack
- 抗体名:
TRPV1 Channel Deluxe Research Pack
- 标记物:
见官方网站
- 宿主:
见 说 明 书
- 适应物种:
见官方网站
- 免疫原:
见官方网站
- 亚型:
见官方网站
- 形态:
液体或冻干粉
- 应用范围:
见官方网站
- 浓度:
见官方网站
- 保存条件:
-20°C
- 规格:
12 Vials
TRPV1 Channel Deluxe Research Pack
All You Need for TRPV1 Channel ResearchCat #: ESD-300
12 Vials
Alomone Labs is pleased to offer the TRPV1 Channel Deluxe Research Pack (#ESD-300). The Research Pack contains all you need for TRPV1 research: Antibodies recognizing different domains of the channel, specific TRPV1 blockers and an activator, all in one economical package!
- Compounds
- Scientific Background
- Related Products
| Product Name | Cat # | Size |
|---|---|---|
Anti-TRPV1 |
ACC-030 | 1 x 0.2 ml |
Guinea pig Anti-TRPV1 |
AGP-118 | 1 x 0.2 ml |
Anti-Rat TRPV1 (extracellular) |
ACC-029 | 1 x 0.2 ml |
Anti-Rat TRPV1 (extracellular)-ATTO-488 |
ACC-029-AG | 1 x 50 µl |
A-889425 |
A-195 | 1 x 10 mg |
Capsaicin |
C-125 | 1 x 250 mg |
Resiniferatoxin |
R-400 | 1 x 1 mg |
SB-366791 |
S-180 | 1 x 25 mg |
Note A Guinea pig polyclonal antibody (#AGP-118) is included in this Research Pack. Please take into account when reacting with a secondary antibody.
Scientific Background
TRPV1 (also named VR1, capsaicin receptor and vanilloid receptor) is a member of the transient receptor potential (TRP) channel family, which includes TRPC, TRPM, TRPA, TRPP, TRPML and the TRPV subfamilies. The TRPV subfamily consists of six members named, TRPV1-6. The TRPV1 channel is a vanilloid gated, nonselective cation channel.
The channel has sequence homology to the TRP family, and shares a similar predicted structure of six transmembrane domain (TM) with a pore loop between TM5 and TM6.1 TRPV1 is expressed predominantly in nociceptors and in sensory neurons.2,3
TRPV1 has many activators among them heat, protons, vanilloids like capsaicin, resiniferatoxin (RTX), and lipids. This channel is associated with tissue injury and inflammation.5,6
TRPV1 Channel Deluxe Research PackReferences
- Gunthorpe, M.J. et al. (2002) Trends Pharmacol. Sci. 23, 183.
- Cesare, P. et al. (1999) Proc. Natl. Acad. Sci. U.S.A. 96, 7658.
- Kim, J. et al. (2003) Nature 424, 81.
- Ahern, G. P. et al. (2003) J. Biol. Chem. 278, 30429.
- Ross, R.A. et al. (2003) Br. J. Pharmacol. 140, 790.
- Tominaga, M. et al. (1998) Neuron 21, 531.
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