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- 详细信息
- 文献和实验
- 技术资料
- 库存:
大量
- 保质期:
12个月
- 供应商:
上海再康生物科技有限公司
- 保存条件:
4-8ºC without exposure to light. No precautions necessary during handling.
- 规格:
200ug/1mg
Anti-Protein S (human)
- Cat. No.
- HYB 232-11
- Product name
- Anti-Protein S (human)
- Description
- Mouse monoclonal antibody
- Specificity
- HYB 232-11 is specific for human protein S.
- Immunogen
- Protein S isolated from human plasma
- Application
- ELISA, WB ( not applicable)
- Species reactivity (positive)
- Human
- Species reactivity (negative)
- Not determined
- Subclass
- IgG2b/k
- Gene ID
- 5627
- Clone number
- 8D5
- Epitope
- Not determined
- Content
- Available in 200 µL and 1 mL size.1 mg/mL +/- 15%. See Certificate of Analysis for details.
- Purification
- Protein-A purified
- Form
- Liquid
- Solvent
- 0.01 M phosphate buffer, pH 7.4, containing 0.5 M NaCl and 15 mM sodium azide
- Storage
- 4-8ºC without exposure to light. No precautions necessary during handling.
- Target
- Protein S is a vitamin K-dependent, potent neutral anticoagulant plasma glycoprotein. Protein S has a molecular weight of approximately 70 kDa and consists of a single polypeptide chain. The concentration of protein S in human plasma is 25 µg/ml, with a half-life of approximately two days. About 40% of protein S in plasma is in a free form, wheraes 60% is complexed with C4b-binding Protein (C4BP). Only the free protein S functions as a cofactor to antigen presenting cells (APC) in the APC-dependent degradation of Factor Va and Factor VIIIa.
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文献和实验Analysis of the Protein S Gene in Protein S Deficiency
Protein S (PS) is a 71-kDa vitamin K-dependent glycoprotein first identified in human plasma by DiScipio and colleagues in 1977 (1 ), a year after the discovery of the anticoagulant protein C (PC) (2 ,3 ). A few years later, Walker
Protein S (PS) is a vitamin K-dependent plasma glycoprotein. Around 60–70% of PS in plasma is noncovalently bound to C4-binding protein (C4BP). Free PS functions as a cofactor that enhances the activity of activated protein C (APC
a simple ELISA method to detect human anti-antibody response.
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