Anti-Protein C (human)

Anti-Protein C (human)

Cat. No.

HYB 237-05

Product name

Anti-Protein C (human)

Description

Mouse monoclonal antibody

Specificity

HYB 237-05 reacts with human protein C.

Immunogen

Protein C isolated from human plasma 

Application

ELISA, WB

Species reactivity (positive)

Human

Species reactivity (negative)

Not determined

Subclass

IgG2b/k

Gene ID

5627

Clone number

3C7

Epitope

Epitope specificity differs from that of HYB 237-01

Content

Available in 200 µL and 1 mL size.1 mg/mL +/- 15%. See Certificate of Analysis for details.

Purification

Protein-A purified

Form

Liquid

Solvent

0.01 M phosphate buffer, pH 7.4, containing 0.5 M NaCl and 15 mM sodium azide

Storage

4-8ºC without exposure to light. No precautions necessary during handling.

Target

Protein C is a vitamin K-dependent serine protease that is produced in the liver and made up of 2 polypeptide chains. The 62 kDa proenzyme is activated by thrombin bound to an endothelial surface receptor and the active enzyme cleaves factor Va and VIIIa inhibitng blood coagulation. The molecular weight of the active enzyme is 55kDa and the normal concentration in human plasma is approximately 1-3 ng/ml while the concentration of the proenzyme is approximately 3 µg/ml due to the very fast turnov