Anti-α-calcitonin gene-related

Anti-α-calcitonin gene-related peptide (α-CGRP)

Cat. No.

ABS 026-04

Product name

Anti-α-calcitonin gene-related peptide (α-CGRP)

Description

Mouse monoclonal antibody

Specificity

ABS 026-04 binds human α-CGRP. Based on inhibition ELISA, ABS 026-04 cross-reacts up to 12% with human b-CGRP and human amylin, while there is little (<4%) cross-reaction with rat α-CGRP.

Immunogen

Synthetic human α-CGRP 

Application

ELISA, WB

Species reactivity (positive)

Human, rat (4%)

Species reactivity (negative)

Not determined

Subclass

IgG1/k

Gene ID

24241

Clone number

4

Epitope

The epitope lies within residues 19-37 of human α-CGRP

Content

Available in 200 µL and 1 mL size.1 mg/mL +/- 15%. See Certificate of Analysis for details.

Purification

Protein-A purified

Form

Liquid

Solvent

0.01 M phosphate buffer, pH 7.4, containing 0.5 M NaCl and 15 mM sodium azide

Storage

4-8ºC without exposure to light. No precautions necessary during handling.

Target

Calcitonin gene-related peptide is a 37 amino acid vasoactive neuropeptide (MW 3789) widely expressed throughout the central and peripheral nervous system. CGRP has potent vasodilatory effects probably serving as a regulator of regional blood flow, in addition to a variety of other cellular effects.