- 询价
- R&D
- ZK-0002882
- 美国/中国
- 2025年11月20日
- 科研使用
- Goat，Rabbit，Mouse
- 人，大鼠，小鼠，兔
1 年钻石会员
企业认证
相关产品推荐更多 >
万千商家帮你免费找货
0 人在求购买到急需产品
- 详细信息
- 技术资料
- 靶点：
来电咨询
- 克隆性：
多克隆
- 标记物：
见 说 明 书
- 宿主：
Goat，Rabbit，Mouse
- 适应物种：
人，大鼠，小鼠，兔
- 形态：
液态/粉状
- 应用范围：
科研使用
- 浓度：
1mg/1ml
- 保存条件：
-20℃保存
- Aph-1aL/C Terminal (245-265) Polyclonal Antibody, Purified保存于运输说明：
- Store at -20°C
- 详细信息：
-
Description Polyclonal Antibody against Aph-1a (Aph-1aL, C-Terminal Region), O2C2 Intended Use **Research Use Only (RUO)**
This product is sold for laboratory research use only, not for human or in-vivo use.Form Affinity Purified Antibody Host Rabbit Species Reactivity Aph-1aL/C Terminal (245-265) Polyclonal Antibody, PurifiedHuman [Ab] 0.3 mg/mL Specificity The gamma secretase is a multiprotein complex consisting of presenilin, nicastrin, Aph-1 and Pen-2; all four proteins are necessary for full proteolytic activity. The gamma secretase complex catalyzes cleavage of a number of integral membrane proteins including Amyloid precursor protein, Notch, Erb4 and E-cadherin. While Aph-1 stabilizes the presenilin holoprotein within the gamma secretase complex, Pen-2 is required for endoproteolysis of presenilin and activation of the gamma secretase. The Aph-1 homologue on human chromosome 1 is termed Aph-1a and on human chromosome 15 is referred to as Aph-1b. The antibody Aph-1aL/C-terminal (O2C2) was raised against the human Aph-1aL/C-terminal region and recognizes the sequence CRRQEDSRVMVYSALRIPPED of human Aph-1aL.
Covance also offers an antibody O2F1 (PRB-551P) which recognizes residues 92-115 of the Aph-1aL/ S Loop.Uses This antibody is effective in immunoblotting and immunofluorescence (IF). Suggested Working Dilution Aph-1aL/C Terminal (245-265) Polyclonal Antibody, PurifiedThe optimal working dilution should be determined for each specific assay condition. This antibody is sold for laboratory research use only, not for human or in-vivo use. Covance antibodies may not be resold or modified for resale without prior written approval. - Western blot: 1:1,000
- IF: 1:200
Storage Store at -20°C. Upon initial thawing, apportion into working aliquots and store at -20°C. Avoid repeated freeze-thaw cycles to prevent denaturing the antibody. For long-term storage, keep the antibody at -80°C. References Gu Y, Chen F, Sanjo N, Kawarai T, Hasegawa H, Duthie M, Li W, Ruan X, Luthra A, Mount HT, Tandon A, Fraser PE, St George-Hyslop P. Aph-1 interacts with mature and immature forms of presenilins and nicastrin and may play a role in maturation of the presenilin.nicastrin complexes. J Biol Chem 278:7374-7380, 2003. Warranty/Conditions Covance products may not be resold or modified for resale without prior written approval. - Aph-1aL/C Terminal (245-265) Polyclonal Antibody, Purified
- zk-4941R CD274程序性死亡配体1抗体
zk-10159R B7-H1/PD-L1/CD274程序性死亡配体1抗体
zk-0107M beta-Amyloid (1-42)β淀粉样肽（1-42）抗体
zkm-4713M beta-Amyloid (1-42)β淀粉样肽（1-42）单克隆抗体
zk-12440R ABCB11胆汁酸盐输出泵/ATP结合盒转运蛋白11抗体
zk-12639R BSPRYBSPRY蛋白抗体
zk-13684R BAIAP2L2BAIAP2L2蛋白抗体
zk-3056R Phospho-Bad (Ser136)磷酸化相关死亡促进因子抗体
zk-3057R Phospho-Bad (Ser155)磷酸化相关死亡促进因子抗体
zk-0953R hCG beta人β亚基人绒毛膜促性腺激素(β HCG)抗体
zk-0729R BK channel钙激活钾通道蛋白 α 1抗体
zk-0868R BK channel钙激活钾通道蛋白 α 1抗体
zk-0910R Batroxobin Protein蛇毒巴曲酶抗体
zk-1153R BidBH3结构域凋亡诱导蛋白抗体
zk-0127R BaxBax抗体
zk-0032R Bcl-2Bcl-2抗体
zk-0248R BDNF脑源神经营养因子抗体
zk-0217R bFGF碱性成纤维细胞生长因子抗体
zk-1015R BRMS-1乳腺癌转移抑制基因1抗体
zk-0292R BSA牛血清白蛋白抗体
zk-0466R Beta-caseinβ-酪蛋白抗体
zk-2455R beta Glucan Receptorβ葡聚糖受体抗体
zk-2143R Batroxobin蛇毒蛋白巴曲酶抗体
zk-2765R BMX非受体性蛋白酪氨酸激酶ETK抗体
zk-3132R Phospho-BMX (Tyr40)磷酸化非受体性蛋白酪氨酸激酶ETK抗体
zk-0893R phospho-BAD (Ser128)磷酸化相关死亡促进因子抗体
zk-8521R BarX1BarX1蛋白抗体
zk-7622R B3GALNT1β1，3半乳糖转移酶3抗体
zk-7620R Band3红细胞阴离子交换蛋白1抗体
zk-6985R BRN3B脑特定蛋白Brn3B抗体
zk-1353R Beclin 1Bcl-2同源结构域蛋白抗体
zk-1374R BMP4骨形态发生蛋白4抗体
zk-9849R BAALC脑和急性白血病胞浆蛋白抗体
zk-9850R BST2骨髓基质干细胞抗原2抗体
风险提示：丁香通仅作为第三方平台，为商家信息发布提供平台空间。用户咨询产品时请注意保护个人信息及财产安全，合理判断，谨慎选购商品，商家和用户对交易行为负责。对于医疗器械类产品，请先查证核实企业经营资质和医疗器械产品注册证情况。
技术资料暂无技术资料 索取技术资料
Aph-1aL/C Terminal (245-265) Polyclonal Antibody, Purified
询价
