BioSIM 抗人 VSIR/VISTA 抗体，生物类似药

BioSIM 抗人 VSIR/VISTA 抗体，科研用途

产品概述

BioSIM抗人VSIR/VISTA抗体是一种高特异性的生物类似药，专为科研用途设计。该抗体靶向人VSIR/VISTA蛋白（V-domain Ig suppressor of T cell activation），是一种重要的免疫检查点分子，在调节免疫应答中扮演关键角色。作为HMBD-002的生物类似药，该抗体采用先进的重组技术在无动物成分环境中生产，确保了高纯度和批次一致性。

生产与纯化

• 在无动物成分的专用设施中生产
• 采用体外无蛋白细胞培养技术
• 经过多步骤纯化过程，包括Protein A/G亲和色谱
• 严格的质量控制流程，确保产品一致性

研究领域与应用

该抗体适用于多种免疫学和癌症研究领域，特别关注以下领域：

• 非小细胞肺癌（NSCLC）：研究免疫检查点在肿瘤微环境中的作用
• 三阴性乳腺癌：探索免疫逃逸机制和潜在治疗靶点
• 实体瘤：分析肿瘤免疫微环境中的免疫调节通路
• 转移癌：研究肿瘤转移过程中的免疫调控机制

应用方法

BioSIM抗人VSIR/VISTA抗体适用于多种实验方法：

• ELISA：用于检测和定量分析VSIR/VISTA蛋白
• FACS：流式细胞术分析VSIR/VISTA在细胞表面的表达
• Functional assay：评估VSIR/VISTA在免疫功能调控中的作用
• Research in vivo：体内研究VSIR/VISTA在疾病模型中的作用机制

产品特性

储存建议

为确保抗体活性和稳定性，请遵循以下储存条件：

• 短期储存（1-2周）：4°C保存
• 中期储存（最长12个月）：-20°C保存
• 长期储存：-80°C保存
• 注意事项：避免反复冻融，建议分装后使用

适用场景

该抗体适用于基础研究、药物筛选机制研究、生物标志物发现以及抗体药物开发前期研究等场景，为科研人员提供高质量的研究工具。

注意：以上信息可能随着产品优化升级等因素产生变动，具体信息请咨询亚科因公司。

BioSIM Anti-Human VSIR/VISTA Antibody, Research Use

Product Overview

BioSIM anti-Human VSIR/VISTA Antibody is a highly specific biosimilar designed for research purposes. This antibody targets human VSIR/VISTA protein (V-domain Ig suppressor of T cell activation), an important immune checkpoint molecule that plays a critical role in regulating immune responses. As a biosimilar of HMBD-002, this antibody is produced using advanced recombinant technology in an animal component-free environment, ensuring high purity and batch-to-batch consistency.

Production and Purification

• Produced in dedicated animal component-free facilities
• Utilizes in vitro protein-free cell culture technology
• Purified through a multi-step process including Protein A/G affinity chromatography
• Strict quality control procedures to ensure product consistency

Research Areas and Applications

This antibody is suitable for various immunology and cancer research fields, with special focus on the following areas:

• Non-Small Cell Lung Cancer (NSCLC): Studying the role of immune checkpoints in the tumor microenvironment
• Triple-Negative Breast Cancer: Exploring immune escape mechanisms and potential therapeutic targets
• Solid Tumors: Analyzing immunomodulatory pathways in the tumor immune microenvironment
• Metastatic Cancer: Investigating immune regulatory mechanisms in the process of tumor metastasis

Application Methods

BioSIM anti-Human VSIR/VISTA Antibody is suitable for various experimental methods:

• ELISA: For detection and quantitative analysis of VSIR/VISTA protein
• FACS: Flow cytometry analysis of VSIR/VISTA expression on cell surfaces
• Functional assay: Evaluating the role of VSIR/VISTA in immune function regulation
• Research in vivo: In vivo studies on the mechanism of action of VSIR/VISTA in disease models

Product Characteristics

Storage Recommendations

To ensure antibody activity and stability, please follow the following storage conditions:

• Short-term storage (1-2 weeks): Store at 4°C
• Medium-term storage (up to 12 months): Store at -20°C
• Long-term storage: Store at -80°C
• Precautions: Avoid repeated freeze-thaw cycles, aliquoting before use is recommended

Applicable Scenarios

This antibody is suitable for basic research, drug screening mechanism studies, biomarker discovery, and preliminary research in antibody drug development, providing researchers with high-quality research tools.

Note: The above information may change due to factors such as product optimization and upgrades. For specific information, please consult Yacoin Biotechnology.