BioSIM 抗人 TSLP 抗体 (特泽鲁单抗)，生物类似

BioSIM 抗人 TSLP 抗体 (特泽鲁单抗)，生物类似药，科研用途

英文名称：BioSIM anti-Human TSLP Antibody (Tezepelumab Biosimilar), Research Grade

CAS号：1572943-04-4

产品货号：SIM0527-5mg

产品规格：5mg

供应商：InvivoCrown

产品概述

BioSIM 抗人 TSLP 抗体 (特泽鲁单抗) 是一种高特异性的生物类似药，专为科研用途设计。该抗体基于特泽鲁单抗(Tezepebumab)的可变区，能够特异性识别并结合人胸腺基质淋巴细胞生成素(Thymic Stromal Lymphopoietin, TSLP)。TSLP是一种与IL-7相关的细胞因子，在上皮细胞、基质细胞、肥大细胞和树突状细胞中表达，通过IL-7Rα/TSLPR受体复合物发挥作用，受NF-κB调控。

技术参数

产品特性

• 产品类型：二抗
• 来源宿主：Human
• 反应性：Human
• 免疫原：请参考该产品的说明书

生物学功能

TSLP在免疫调节中发挥关键作用，能够驱动Th2细胞分化，这与特应性皮炎和哮喘等疾病密切相关。此外，TSLP还能影响B细胞、调节性T细胞和嗜碱性粒细胞的活性。原始的Tezepelumab通过阻断TSLP受体结合来治疗中重度哮喘，而此科研级抗体可用于相关机制研究。

研究领域与应用

主要研究领域

该抗体主要应用于哮喘相关研究，特别适合探索TSLP在炎症反应和免疫调节中的作用机制。

应用类型

• ELISA (酶联免疫吸附测定)
• FACS (流式细胞术)
• Functional assay (功能检测)
• Research in vivo (体内研究)

保存与处理

为确保产品质量和稳定性，请遵循以下保存建议：

• 避免反复冻融，以保持抗体活性
• 短期保存(1-2周)：4°C
• 中期保存：-20°C，最长12个月
• 长期保存：-80°C

使用前请平衡至室温，避免剧烈震荡。开封后请尽快使用，避免污染。

订购信息

如需订购或了解更多产品信息，请联系我们的销售团队。产品仅供科研使用，不可用于临床诊断或治疗。

注意：以上信息可能随着产品优化升级等因素产生变动，具体信息请咨询亚科因公司。

BioSIM anti-Human TSLP Antibody (Tezepelumab Biosimilar), Research Grade

English Name: BioSIM anti-Human TSLP Antibody (Tezepelumab Biosimilar), Research Grade

CAS Number: 1572943-04-4

Catalog Number: SIM0527-5mg

Product Size: 5mg

Supplier: InvivoCrown

Product Overview

BioSIM anti-Human TSLP Antibody (Tezepelumab Biosimilar) is a highly specific biosimilar designed for research purposes. This antibody is based on the variable region of Tezepelumab and can specifically recognize and bind to human Thymic Stromal Lymphopoietin (TSLP). TSLP is an IL-7-related cytokine expressed in epithelial cells, stromal cells, mast cells, and dendritic cells, functioning through the IL-7Rα/TSLPR receptor complex and regulated by NF-κB.

Technical Parameters

Product Characteristics

• Product Type: Secondary Antibody
• Host: Human
• Reactivity: Human
• Immunogen: Please refer to the product manual

Biological Function

TSLP plays a critical role in immune regulation, driving Th2 cell differentiation, which is closely related to diseases such as atopic dermatitis and asthma. Additionally, TSLP can also affect the activity of B cells, regulatory T cells, and basophils. The original Tezepelumab treats moderate to severe asthma by blocking TSLP receptor binding, while this research-grade antibody can be used for related mechanism studies.

Research Fields and Applications

Main Research Fields

This antibody is mainly applied to asthma-related research, especially suitable for exploring the mechanism of TSLP in inflammatory responses and immune regulation.

Application Types

• ELISA (Enzyme-Linked Immunosorbent Assay)
• FACS (Flow Cytometry)
• Functional assay
• Research in vivo

Storage and Handling

To ensure product quality and stability, please follow the storage recommendations below:

• Avoid repeated freeze-thaw cycles to maintain antibody activity
• Short-term storage (1-2 weeks): 4°C
• Medium-term storage: -20°C, up to 12 months
• Long-term storage: -80°C

Balance to room temperature before use, avoid vigorous shaking. Use as soon as possible after opening to avoid contamination.

Ordering Information

For ordering or more product information, please contact our sales team. This product is for research use only and not for clinical diagnosis or treatment.

Note: The information above may change due to factors such as product optimization and upgrades. Please consult Yacoin Company for specific information.