BioSIM 抗人 SOST/Sclerostin 抗体 (

BioSIM 抗人 SOST/Sclerostin 抗体 (布索组单抗)，生物类似药

产品基本信息

产品概述

BioSIM 抗人 SOST/Sclerostin 抗体是一种高特异性的生物类似药，靶向作用于人源SOST/Sclerostin蛋白。SOST/Sclerostin是一种由骨细胞分泌的糖蛋白，是骨形成过程中的重要调节因子。该抗体作为布索组单抗的生物类似药，为骨质疏松症及相关骨代谢疾病的研究提供了有力的工具。

技术特点与生产工艺

• 无动物成分生产：该抗体在无动物成分的设施中生产，尽可能减少动物源污染风险
• 无蛋白细胞培养技术：采用体外无蛋白细胞培养系统，确保产品纯净度和批次一致性
• 多步骤纯化工艺：经过包括Protein A或G亲和色谱在内的多步骤纯化过程，确保抗体高纯度
• 人源化设计：来源于Humanized宿主，具有更好的生物相容性和更低免疫原性

应用领域

该抗体主要应用于骨质疏松症及相关骨代谢疾病的研究领域，具体应用包括：

• ELISA分析：用于检测样本中SOST/Sclerostin蛋白的表达水平
• 流式细胞术(FACS)：用于细胞表面SOST/Sclerostin蛋白的检测与分析
• 功能性实验：研究SOST/Sclerostin在骨形成过程中的调控机制
• 体内研究：用于动物模型中骨质疏松症的机制研究与药物评估

技术参数

储存与稳定性

• 避免反复冻融：为保持抗体活性，请避免反复冻融
• 短期储存：1-2周内在4°C条件下保存
• 中期储存：最长12个月请在-20°C条件下保存
• 长期储存：长期保存建议在-80°C条件下
• 注意事项：使用前请平衡至室温，避免剧烈震荡

订购信息

产品货号：SIM0520-5mg
规格：5mg
供应商：InvivoCrown

注意：以上信息可能随着产品优化升级等因素产生变动，具体信息请咨询亚科因公司。

BioSIM anti-Human SOST/Sclerostin Antibody (Blosozumab Biosimilar)

Product Basic Information

Product Overview

BioSIM anti-Human SOST/Sclerostin Antibody is a highly specific biosimilar that targets human SOST/Sclerostin protein. SOST/Sclerostin is a glycoprotein secreted by osteocytes and an important regulatory factor in the bone formation process. As a biosimilar of Blosozumab, this antibody provides a powerful tool for research on osteoporosis and related bone metabolic diseases.

Technical Features and Production Process

• Animal Component-Free Production: This antibody is produced in animal component-free facilities to minimize the risk of animal-derived contamination
• Protein-Free Cell Culture Technology: Utilizes in vitro protein-free cell culture systems to ensure product purity and batch consistency
• Multi-step Purification Process: Undergoes a multi-step purification process including Protein A or G affinity chromatography to ensure high antibody purity
• Humanized Design: Derived from Humanized host with better biocompatibility and lower immunogenicity

Application Areas

This antibody is mainly used in the research field of osteoporosis and related bone metabolic diseases, with specific applications including:

• ELISA Analysis: For detecting the expression level of SOST/Sclerostin protein in samples
• Flow Cytometry (FACS): For detection and analysis of cell surface SOST/Sclerostin protein
• Functional Assays: For studying the regulatory mechanisms of SOST/Sclerostin in the bone formation process
• In Vivo Studies: For mechanism research and drug evaluation of osteoporosis in animal models

Technical Parameters

Storage and Stability

• Avoid repeated freeze-thaw cycles: To maintain antibody activity, please avoid repeated freeze-thaw cycles
• Short-term Storage: Store at 4°C for 1-2 weeks
• Medium-term Storage: Store at -20°C for up to 12 months
• Long-term Storage: For long-term storage, it is recommended to store at -80°C
• Precautions: Equilibrate to room temperature before use and avoid vigorous shaking

Ordering Information

Product Number: SIM0520-5mg
Specification: 5mg
Supplier: InvivoCrown

Note: The above information may change due to factors such as product optimization and upgrades. For specific information, please consult Yaokeen Company.