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- 文献和实验
- 技术资料
- 免疫原:
该BioSIM 抗人 CD4 抗体 (曲利组单抗),生物类似药,科研用途 [ CAS: 1207446-68-1]的免疫原请参考该产品的说明书
- 保存条件:
为确保适当储存,请避免反复冻融。短期需求(1-2周)请在4°C下保存;最长12个月的储存请在-20°C下保存。长期储存请在-80°C下保存。
- 克隆性:
单克隆
- 适应物种:
Human
- 保质期:
为确保适当储存,请避免反复冻融。短期需求(1-2周)请在4°C下保存;最长12个月的储存请在-20°C下保存。长期储存请在-80°C下保存。
- 级别:
科研级别
- 库存:
999
- 供应商:
亚科因(Abbkine)
- 宿主:
Humanized
- 应用范围:
ELISA, FACS, Functional assay, Research in vivo
- 抗体英文名:
CD4
- 抗体名:
CD4
- 规格:
5mg
BioSIM 抗人 CD4 抗体 (曲利组单抗生物类似药)
科研级高特异性抗体 - 产品规格:5mg
| 产品货号 | SIM0375-5mg |
| 供应商 | InvivoCrown |
| CAS号 | 1207446-68-1 |
| 产品类型 | 二抗 |
| 来源宿主 | 人源化 (Humanized) |
| 反应性 | 人源 (Human) |
产品概述
BioSIM 抗人 CD4 抗体是一种高纯度的科研级抗体,作为曲利组单抗(Tregalizumab)的生物类似药,专为研究人员设计。该抗体特异性识别人类CD4分子,适用于多种免疫学研究应用,包括T细胞功能分析、免疫调节机制研究及相关疾病模型建立。
技术特点与优势
- 无动物成分生产:在完全无动物成分的生产设施中合成,确保批次间一致性并减少潜在交叉污染风险
- 无蛋白细胞培养技术:采用先进的体外无蛋白细胞培养系统,避免传统动物源培养基可能带来的杂质
- 多步骤纯化工艺:经过包括Protein A/G亲和色谱在内的多步纯化程序,确保高纯度和低内毒素水平
- 人源化设计:优化的人源化结构降低非特异性结合,提高实验特异性和可重复性
研究领域与应用
主要研究领域
- 哮喘发病机制研究
- 药物超敏反应分析
- Treg细胞功能调控
- 自身免疫性疾病模型
应用类型
- ELISA:适用于CD4蛋白定量检测和ELISA试剂盒开发
- FACS:流式细胞术分析CD4+ T细胞亚群和表面标志物
- Functional assay:功能性实验,如T细胞激活、抑制和分化研究
- Research in vivo:动物模型研究,评估免疫干预效果
技术参数
| 抗体亚型 | 请参考产品说明书 |
| 免疫原 | 请参考产品说明书 |
| 纯度 | ≥95% (SDS-PAGE分析) |
| 浓度 | 请参考产品说明书 |
| 缓冲液成分 | 请参考产品说明书 |
储存条件与稳定性
- 避免反复冻融:为确保抗体活性,请避免多次冻融循环
- 短期储存:1-2周内使用,可在4°C保存
- 中期储存:最长12个月,建议在-20°C保存
- 长期储存:超过12个月,请在-80°C条件下保存
- 注意事项:每次使用后请立即 aliquot 分装并返回适当温度保存
使用建议
本抗体为科研用途设计,不用于临床诊断或治疗。建议在使用前进行小规模测试以确定最佳实验条件。不同应用的最佳稀释比例请参考相关文献或进行预实验确定。如需技术支持,请联系我们的专业技术团队。
注意:以上信息可能随着产品优化升级等因素产生变动,具体信息请咨询亚科因公司。

BioSIM Anti-Human CD4 Antibody (Tregalizumab Biosimilar)
Research Grade High Specificity Antibody - Product Specification: 5mg
| Catalog Number | SIM0375-5mg |
| Supplier | InvivoCrown |
| CAS Number | 1207446-68-1 |
| Product Type | Primary Antibody |
| Host Species | Humanized |
| Reactivity | Human |
Product Overview
BioSIM Anti-Human CD4 Antibody is a high-purity research grade antibody designed as a biosimilar of Tregalizumab, specifically for researchers. This antibody specifically recognizes human CD4 molecules and is suitable for various immunological research applications, including T cell functional analysis, immunomodulation mechanism studies, and establishment of related disease models.
Technical Features and Advantages
- Animal Component-Free Production: Synthesized in completely animal component-free production facilities, ensuring batch-to-batch consistency and reducing potential cross-contamination risks
- Protein-Free Cell Culture Technology: Utilizes advanced in vitro protein-free cell culture systems to avoid impurities that may be present in traditional animal-derived culture media
- Multi-step Purification Process: Undergoes multi-step purification procedures including Protein A/G affinity chromatography to ensure high purity and low endotoxin levels
- Humanized Design: Optimized humanized structure reduces non-specific binding, enhancing experimental specificity and reproducibility
Research Fields and Applications
Primary Research Fields
- Asthma pathogenesis research
- Drug hypersensitivity analysis
- Treg cell functional regulation
- Autoimmune disease models
Application Types
- ELISA: Suitable for quantitative detection of CD4 protein and ELISA kit development
- FACS: Flow cytometry analysis of CD4+ T cell subsets and surface markers
- Functional assay: Functional experiments such as T cell activation, inhibition, and differentiation studies
- Research in vivo: Animal model studies to evaluate immune intervention effects
Technical Parameters
| Antibody Isotype | Please refer to product manual |
| Immunogen | Please refer to product manual |
| Purity | ≥95% (by SDS-PAGE analysis) |
| Concentration | Please refer to product manual |
| Buffer Components | Please refer to product manual |
Storage Conditions and Stability
- Avoid repeated freeze-thaw cycles: To maintain antibody activity, please avoid multiple freeze-thaw cycles
- Short-term storage: For use within 1-2 weeks, can be stored at 4°C
- Medium-term storage: Up to 12 months, storage at -20°C is recommended
- Long-term storage: For more than 12 months, please store at -80°C
- Important note: After each use, please immediately aliquot and return to appropriate storage temperature
Usage Recommendations
This antibody is designed for research purposes only and is not intended for clinical diagnosis or treatment. It is recommended to conduct small-scale testing before use to determine optimal experimental conditions. For optimal dilution ratios for different applications, please refer to relevant literature or perform preliminary experiments. For technical support, please contact our professional technical team.
Note: The above information may change due to factors such as product optimization and upgrades. For specific information, please consult Yacoin company.
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