BioSIM 抗人 CD221/IGF1R 抗体 (西妥木单

BioSIM 抗人 CD221/IGF1R 抗体 (西妥木单抗) 生物类似药

产品货号：SIM0828-1mg

产品规格：1mg

CAS号：947687-12-9

产品类型：二抗

供应商：InvivoCrown

产品概述

BioSIM 抗人 CD221/IGF1R 抗体是一种西妥木单抗的生物类似药，专用于科研领域。该产品靶向人CD221/IGF1R（胰岛素样生长因子1受体），这是一种在多种癌症研究中具有重要意义的靶点。IGF1R属于受体酪氨酸激酶家族，在细胞增殖、分化和凋亡过程中发挥关键作用，特别是在食道癌、食道腺癌和食管鳞状细胞癌等恶性肿瘤中表现出异常表达。

生产工艺

本产品为重组生物类似抗体，采用先进的生产工艺制造。该抗体在无动物成分的设施中生产，仅使用体外的无蛋白细胞培养技术，确保产品的一致性和纯度。生产过程中采用多步骤纯化工艺，其中包括Protein A或G的色谱工艺，以获得高纯度的最终产品。

应用领域

BioSIM 抗人 CD221/IGF1R 抗体适用于多种科研应用，包括：

• ELISA：可用于检测和定量IGF1R蛋白表达水平
• FACS：适用于流式细胞术分析，可检测细胞表面IGF1R的表达
• Functional assay：可用于研究IGF1R在细胞信号传导中的功能
• Research in vivo：适用于动物模型研究，探索IGF1R在肿瘤发生发展中的作用

产品特性

• 来源宿主：Human
• 反应性：Human
• 免疫原：具体免疫原信息请参考产品说明书
• 研究领域：食道癌，食道腺癌，食管鳞状细胞癌

保存条件

为确保产品的稳定性和活性，请遵循以下保存建议：

• 短期保存（1-2周）：4°C条件下保存
• 中期保存（最长12个月）：-20°C条件下保存
• 长期保存：-80°C条件下保存

注意：为避免产品活性降低，请避免反复冻融。建议分装保存，每次使用只取出所需量。

使用提示

本产品仅供科研用途，不得用于诊断或治疗。具体实验条件建议用户根据自身实验系统进行优化。有关产品详细信息，请参考产品说明书或联系技术支持部门。

注意：以上信息可能随着产品优化升级等因素产生变动，具体信息请咨询亚科因公司。

BioSIM Anti-Human CD221/IGF1R Antibody (Cetuximab) Biosimilar

Catalog Number:SIM0828-1mg

Specifications:1mg

CAS Number:947687-12-9

Product Type:Primary Antibody

Supplier:InvivoCrown

Product Overview

BioSIM Anti-Human CD221/IGF1R Antibody is a biosimilar of Cetuximab, specifically designed for research applications. This product targets human CD221/IGF1R (Insulin-like Growth Factor 1 Receptor), which is a significant target in various cancer studies. IGF1R belongs to the receptor tyrosine kinase family and plays a crucial role in cell proliferation, differentiation, and apoptosis processes, showing abnormal expression in malignant tumors such as esophageal cancer, esophageal adenocarcinoma, and esophageal squamous cell carcinoma.

Production Process

This product is a recombinant biosimilar antibody manufactured using advanced production techniques. The antibody is produced in animal component-free facilities using only protein-free in vitro cell culture technology to ensure product consistency and purity. The production process employs a multi-step purification process, including Protein A or G chromatography, to obtain a high-purity final product.

Application Fields

BioSIM Anti-Human CD221/IGF1R Antibody is suitable for various research applications, including:

• ELISA: Can be used to detect and quantify IGF1R protein expression levels
• FACS: Suitable for flow cytometry analysis to detect cell surface IGF1R expression
• Functional assay: Can be used to study the function of IGF1R in cell signaling
• Research in vivo: Suitable for animal model studies to explore the role of IGF1R in tumorigenesis and development

Product Features

• Host:Human
• Reactivity:Human
• Immunogen:For specific immunogen information, please refer to the product manual
• Research Areas:Esophageal cancer, Esophageal adenocarcinoma, Esophageal squamous cell carcinoma

Storage Conditions

To ensure product stability and activity, please follow the storage recommendations below:

• Short-term storage (1-2 weeks):Store at 4°C
• Medium-term storage (up to 12 months):Store at -20°C
• Long-term storage:Store at -80°C

Note:To avoid reduced product activity, avoid repeated freeze-thaw cycles. It is recommended to aliquot and store, only removing the required amount for each use.

Usage Instructions

This product is for research use only and is not intended for diagnostic or therapeutic purposes. Specific experimental conditions should be optimized by users according to their own experimental systems. For detailed product information, please refer to the product manual or contact the technical support department.

Note: The above information may change due to factors such as product optimization and upgrades. Please consult Yacoin Biotechnology for specific information.