BioSIM 抗人 CD140b/PDGFRB 抗体 (利努

BioSIM anti-Human CD140b/PDGFRB Antibody (Rinucumab Biosimilar)

中文名称：BioSIM 抗人 CD140b/PDGFRB 抗体 (利努苏单抗)，生物类似药，科研用途

核心参数

• 产品货号：SIM0803-1mg
• 产品规格：1mg
• CAS号：1569263-06-4
• 供应商：InvivoCrown
• 抗体类型：一抗 (注：根据其靶向特定抗原的特性，推断为一抗)
• 来源宿主：Human
• 反应性：Human

产品概述

本产品是一款科研级别的利努苏单抗 生物类似药，专为靶向人源CD140b/PDGFRB（血小板衍生生长因子受体β）而设计。该抗体在无动物成分的设施中，采用先进的体外无蛋白细胞培养技术进行生产，并经过包含Protein A/G亲和层析在内的多步骤纯化工艺，以确保产品的批次一致性和高纯度。

应用领域

本产品是进行相关生命科学研究的理想工具，主要应用于以下领域：

• 研究方向：年龄相关性黄斑变性 (AMD)、湿性黄斑变性 (wAMD) 等血管生成相关疾病的研究。
• 应用类型：ELISA、流式细胞术 (FACS)、功能性分析、体内研究。

产品特性

• 生物类似药设计：作为利努苏单抗的生物类似药，本产品旨在提供与参考抗体相似的结合特性和生物学功能，为科研工作提供可靠且经济的选择。
• 高纯度生产工艺：通过多步纯化流程，特别是Protein A/G色谱技术，有效去除杂质，保障实验结果的准确性。
• 无动物源生产体系：生产过程不涉及任何动物源性成分，降低了外源因子（如病毒、支原体）污染的风险，同时提高了产品批次间的稳定性。
• 人源化抗体：抗体来源于人源宿主，可减少在动物模型或细胞实验中的非特异性反应，提高实验的相关性。

储存与处理

为确保产品活性，请遵循以下储存建议：

• 短期储存：对于1-2周内使用的抗体，可于4°C条件下保存。
• 长期储存：推荐在-20°C下保存，有效期最长可达12个月。为达到最佳长期稳定性，建议储存于-80°C。
• 重要提示：请务必避免反复冻融，建议分装后保存。

重要声明

请注意：本产品为科研级别试剂，仅用于实验室研究目的，不得用于诊断、治疗或任何人体应用。

注意：以上信息可能随着产品优化升级等因素产生变动，具体信息请咨询亚科因公司。

BioSIM anti-Human CD140b/PDGFRB Antibody (Rinucumab Biosimilar)

Chinese Name: BioSIM anti-Human CD140b/PDGFRB Antibody (Rinucumab Biosimilar), for Research Use

Core Parameters

• Product Number: SIM0803-1mg
• Product Specification: 1mg
• CAS Number: 1569263-06-4
• Supplier: InvivoCrown
• Antibody Type: Primary Antibody (Note: Inferred as primary antibody based on its targeting of specific antigens)
• Source Host: Human
• Reactivity: Human

Product Overview

This product is a research-grade Rinucumab Biosimilar specifically designed to target human CD140b/PDGFRB (Platelet-Derived Growth Factor Receptor beta). The antibody is produced in animal-free facilities using advanced animal-free cell culture technology and undergoes a multi-step purification process including Protein A/G affinity chromatography to ensure batch consistency and high purity.

Application Areas

This product is an ideal tool for conducting related life science research, mainly used in the following fields:

• Research Areas: Studies on angiogenesis-related diseases such as Age-related Macular Degeneration (AMD), Wet Macular Degeneration (wAMD).
• Application Types: ELISA, Flow Cytometry (FACS), Functional Analysis, In Vivo Studies.

Product Features

• Biosimilar Design: As a biosimilar of Rinucumab, this product aims to provide similar binding characteristics and biological functions as the reference antibody, offering a reliable and economical choice for research work.
• High-Purity Production Process: Through multi-step purification processes, especially Protein A/G chromatography, impurities are effectively removed to ensure the accuracy of experimental results.
• Animal-Free Production System: The production process does not involve any animal-derived components, reducing the risk of contamination by exogenous factors (such as viruses, mycoplasma) while improving the stability between product batches.
• Humanized Antibody: The antibody is derived from a human source host, which can reduce non-specific reactions in animal models or cell experiments and improve the relevance of experiments.

Storage and Handling

To ensure product activity, please follow the following storage recommendations:

• Short-term Storage: For antibodies to be used within 1-2 weeks, they can be stored at 4°C.
• Long-term Storage: It is recommended to store at -20°C, with a validity period of up to 12 months. For optimal long-term stability, storage at -80°C is recommended.
• Important Note: Please avoid repeated freeze-thaw cycles; aliquoting before storage is recommended.

Important Statement

Please Note: This product is a research-grade reagent and is intended for laboratory research purposes only. It must not be used for diagnosis, treatment, or any human applications.

Note: The information above may change due to factors such as product optimization and upgrades. For specific information, please consult Yacoin Company.