BioSIM 抗人 Factor IXa x Factor

BioSIM 抗人 Factor IXa x Factor X 双特异性抗体 (艾美赛珠单抗生物类似药)

产品概述

BioSIM anti-Human Factor IXa x Factor X Bispecific Antibody (Emicizumab Biosimilar), Research Grade 是一种高特异性双抗体分子，能够同时结合人类凝血因子IXa和X，专为血友病研究领域设计。该产品作为科研级别的生物类似药，为研究人员提供了一种经济高效的工具，用于探索凝血机制及开发新型治疗方案。

产品特性与技术优势

• 双特异性设计：能够同时结合Factor IXa和Factor X，模拟内源性凝血八因子辅助功能
• 人源化来源：Humanized来源宿主，提高实验稳定性
• 无动物成分生产：在无动物成分的设施中生产，减少潜在污染风险
• 高纯度保证：采用Protein A或G色谱工艺进行多步骤纯化，确保抗体纯度
• 无蛋白细胞培养：仅使用体外无蛋白细胞培养技术，避免动物源性成分干扰

研究领域与应用

本产品专为科研用途设计，适用于多种实验技术平台：

• ELISA：用于检测凝血因子相互作用及药物靶点结合研究
• FACS：流式细胞术分析凝血因子表达及细胞表面结合情况
• Functional assay：功能测定评估抗体对凝血通路的影响
• Research in vivo：体内研究探索凝血机制及潜在治疗策略

主要应用于血友病相关研究，包括凝血机制基础研究和生物类似药研发与评估。

产品规格与包装

产品货号	SIM0320-5mg
产品规格	5mg
CAS号	1610943-06-0
供应商	InvivoCrown

储存与稳定性

为确保产品活性和稳定性，请遵循以下储存条件：

• 避免反复冻融：多次冻融可能导致抗体活性降低
• 短期储存（1-2周）：4°C保存
• 中期储存（最长12个月）：-20°C保存
• 长期储存：-80°C保存

使用建议

为确保最佳实验结果，建议：

• 使用前轻轻离心，确保抗体溶液集中在管底
• 避免剧烈震荡，防止蛋白变性
• 使用无菌技术操作，防止微生物污染
• 根据具体实验需求优化抗体浓度和孵育条件
• 免疫原性相关信息请参考产品说明书

注意事项

本产品仅限科研用途，不可用于临床诊断或治疗。实验前请仔细阅读产品说明书，并根据实验室安全规范进行操作。

注意：以上信息可能随着产品优化升级等因素产生变动，具体信息请咨询亚科因公司。

BioSIM Anti-Human Factor IXa x Factor X Bispecific Antibody (Emicizumab Biosimilar)

Product Overview

BioSIM anti-Human Factor IXa x Factor X Bispecific Antibody (Emicizumab Biosimilar), Research Grade is a highly specific bispecific antibody molecule capable of simultaneously binding to human coagulation factors IXa and X, designed specifically for hemophilia research. This research-grade biosimilar provides researchers with a cost-effective tool for exploring coagulation mechanisms and developing novel therapeutic approaches.

Product Features and Technical Advantages

• Bispecific Design: Capable of simultaneously binding Factor IXa and Factor X, mimicking the cofactor function of endogenous coagulation factor VIII
• Humanized Source: Derived from humanized host cells to enhance experimental stability
• Animal Component-Free Production: Produced in animal component-free facilities to reduce potential contamination risks
• High Purity Guarantee: Purified through multi-step processes using Protein A or G chromatography to ensure antibody purity
• Protein-Free Cell Culture: Utilizes only in vitro protein-free cell culture technology to avoid interference from animal-derived components

Research Areas and Applications

This product is designed for research purposes and is suitable for various experimental platforms:

• ELISA: For detecting coagulation factor interactions and drug target binding studies
• FACS: Flow cytometry analysis of coagulation factor expression and cell surface binding
• Functional assay: Functional assessment to evaluate the antibody's effect on coagulation pathways
• Research in vivo: In vivo studies exploring coagulation mechanisms and potential therapeutic strategies

Primarily applied in hemophilia-related research, including basic coagulation mechanism studies and biosimilar development and evaluation.

Product Specifications and Packaging

Product Number	SIM0320-5mg
Product Specification	5mg
CAS Number	1610943-06-0
Supplier	InvivoCrown

Storage and Stability

To maintain product activity and stability, please follow the storage conditions below:

• Avoid repeated freeze-thaw cycles: Multiple freeze-thaw cycles may reduce antibody activity
• Short-term storage (1-2 weeks): Store at 4°C
• Medium-term storage (up to 12 months): Store at -20°C
• Long-term storage: Store at -80°C

Usage Recommendations

For optimal experimental results, we recommend:

• Gently centrifuge before use to ensure the antibody solution is concentrated at the bottom of the tube
• Avoid vigorous shaking to prevent protein denaturation
• Use aseptic techniques during handling to prevent microbial contamination
• Optimize antibody concentration and incubation conditions based on specific experimental requirements
• For immunogenicity-related information, please refer to the product manual

Precautions

This product is for research use only and is not intended for clinical diagnosis or therapy. Please read the product manual carefully before use and follow laboratory safety protocols.

Note: The above information may be subject to change due to product optimization and upgrades. For specific information, please consult Yakin Company.