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- 免疫原:
该BioSIM 抗人 TROP2 抗体 (戈沙妥珠单抗 / 沙西妥珠单抗),生物类似药,科研用途 [ CAS: 1796566-95-4]的免疫原请参考该产品的说明书
- 保存条件:
为确保适当储存,请避免反复冻融。短期需求(1-2周)请在4°C下保存;最长12个月的储存请在-20°C下保存。长期储存请在-80°C下保存。
- 克隆性:
单克隆
- 适应物种:
Human
- 保质期:
为确保适当储存,请避免反复冻融。短期需求(1-2周)请在4°C下保存;最长12个月的储存请在-20°C下保存。长期储存请在-80°C下保存。
- 级别:
科研级别
- 库存:
999
- 供应商:
亚科因(Abbkine)
- 宿主:
Humanized
- 应用范围:
ELISA, FACS, Functional assay, Research in vivo
- 抗体英文名:
TROP2
- 抗体名:
TROP2
- 规格:
1mg
BioSIM 抗人 TROP2 抗体 (戈沙妥珠单抗 / 沙西妥珠单抗),生物类似药,科研用途
英文名称:BioSIM anti-Human TROP2 Antibody (Sacituzumab Biosimilar), Research Grade
CAS号:1796566-95-4
产品基本信息
- 供应商:InvivoCrown
- 产品货号:SIM0072-1mg
- 产品规格:1mg
- 产品类型:二抗
- 来源宿主:Humanized(人源化)
- 反应性:Human(人)
背景资料
本产品为戈沙妥珠单抗(Sacituzumab)的生物类似药抗体,与治疗性药物Sacituzumab共享可变区,适配科研研究场景。
Sacituzumab是一种完全人源化IgG1κ单克隆抗体,靶向人TROP-2(肿瘤相关靶点)。TROP-2可与紧密连接蛋白-1/7等配体结合,上调细胞信号传导,同时是滋养层干细胞标志物,在胶质母细胞瘤、乳腺癌等肿瘤中呈高表达,也是免疫治疗的潜在靶点。
近期研究中,该靶点相关的ADC(如Sacituzumab Govitecan)已被用于临床前研究,为本产品的科研应用提供了方向参考。
研究领域:三阴性乳腺癌(TNBC)、小细胞肺癌(SCLC)
应用类型
- ELISA(酶联免疫吸附实验)
- FACS(荧光激活细胞分选)
- Functional assay(功能实验)
- Research in vivo(体内研究)
保存建议
为保障产品稳定性,需遵循以下储存条件:
- 短期需求(1-2周):4°C避光保存
- 最长12个月储存:-20°C避光保存
- 长期储存:-80°C避光保存
- 关键注意:避免反复冻融,以防抗体活性下降
注意事项
本产品仅供科研用途,不用于临床诊断/治疗、食品/化妆品或家用场景。使用前请参考产品说明书中的免疫原信息及详细操作指南。
注意:以上信息可能随着产品优化升级等因素产生变动,具体信息请咨询亚科因公司。

BioSIM anti-Human TROP2 Antibody (Sacituzumab), Biosimilar, Research Use
英文名称:BioSIM anti-Human TROP2 Antibody (Sacituzumab Biosimilar), Research Grade
CAS No.: 1796566-95-4
Product Basic Information
- Supplier: InvivoCrown
- Catalog Number: SIM0072-1mg
- Size: 1mg
- Product Type: Secondary Antibody
- Host Source: Humanized
- Reactivity: Human
Background Information
This product is a biosimilar antibody of Sacituzumab, sharing the variable region with the therapeutic drug Sacituzumab, suitable for scientific research applications.
Sacituzumab is a fully humanized IgG1κ monoclonal antibody that targets human TROP-2 (tumor-associated target). TROP-2 can bind to ligands such as tight junction protein-1/7, upregulating cell signal transduction. It is also a trophoblast stem cell marker, highly expressed in tumors such as glioblastoma and breast cancer, and is a potential target for immunotherapy.
In recent studies, ADCs related to this target (such as Sacituzumab Govitecan) have been used in preclinical research, providing direction for the scientific application of this product.
Research Areas: Triple-Negative Breast Cancer (TNBC), Small Cell Lung Cancer (SCLC)
Application Types
- ELISA (Enzyme-Linked Immunosorbent Assay)
- FACS (Fluorescence-Activated Cell Sorting)
- Functional Assay
- In Vivo Research
Storage Recommendations
To ensure product stability, please follow the storage conditions below:
- Short-term (1-2 weeks): Store at 4°C, protected from light
- Up to 12 months storage: Store at -20°C, protected from light
- Long-term storage: Store at -80°C, protected from light
- Key note: Avoid repeated freeze-thaw cycles to prevent decline in antibody activity
Precautions
This product is for research use only, not for use in clinical diagnosis/therapy, food/cosmetics, or household applications. Please refer to the immunogen information and detailed operating guidelines in the product manual before use.
Note: The above information may be subject to change due to product optimization and upgrades. For specific information, please contact InvivoCrown.
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