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- 详细信息
- 文献和实验
- 技术资料
- 抗体名:
Anti-EBNA 3B antibody
- 应用范围:
仅用科研
- 保质期:
见瓶身
- 库存:
99
- 供应商:
嘉兴亦高
- 保存条件:
-20°
- 规格:
250ug
The Epstein-Barr nuclear antigen 3B often referred to as EBNA 3B is a protein expressed by the Epstein-Barr virus (EBV). This protein is encoded within the EBV genome and shows an approximate molecular weight of 115 kDa. EBNA 3B is mainly expressed in EBV-infected B cells and plays a role in modulating the viral latent phase. It acts as a transcriptional regulator influencing the expression of both viral and host genes. Researchers also know the target by its role in latency and cellular transformation distinguishing it from other EBNA proteins./
Biological function summary/
EBNA 3B contributes to the persistence of the virus in the host by modulating immune responses. It belongs to the EBNA 3 family which includes EBNA 3A and EBNA 3C forming a complex important for proper function. EBNA 3B modifies the host's cell cycle control and apoptosis aiding to maintain the viral latency essential for EBV survival and replication. This manipulation of the host cell environment ensures EBV evasion from immune system detection solidifying its role in persistent infection./
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文献和实验该产品被引用文献
PLoS pathogens 16:e1008105 | PubMed 32092124
2020
Proteasomal inhibition triggers viral oncoprotein degradation via autophagy-lysosomal pathway.
out
Applications
Unspecified application
Species
Unspecified reactive species
Chandrima Gain, Samaresh Malik, Shaoni Bhattacharjee, Arijit Ghosh, Erle S Robertson, Benu Brata Das, Abhik Saha
技术资料暂无技术资料 索取技术资料
文献支持
ab16127-250ug,Anti-EBNA 3B antibody
¥3215




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