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- 详细信息
- 文献和实验
- 技术资料
- 抗体名:
Anti-EBNA 3A antibody
- 应用范围:
仅用科研
- 保质期:
见瓶身
- 库存:
99
- 供应商:
嘉兴亦高
- 保存条件:
-20°
- 规格:
250ug
EBNA 3A also known as Epstein-Barr Nuclear Antigen 3A is a protein associated with the Epstein-Barr virus (EBV). This protein has a mass of approximately 115 kDa and is expressed in host cells infected with EBV. EBNA 3A functions as a transcriptional regulator by interacting with DNA and modulating gene expression. EBNA 3A is critical for viral latency and is expressed within the nuclei of infected B lymphocytes contributing to the persistence of the virus within host cells./
Biological function summary/
EBNA 3A modulates the host cell cycle and contributes to the immortalization of infected B cells. EBNA 3A EBNA 3B and EBNA 3C form a complex that regulates viral and cellular genes. This complex plays roles in transcriptional repression and activation affecting cell growth and transformation. Through these mechanisms EBNA 3A influences immune evasion by the virus as EBV can maintain a state of latency and avoid detection by the host immune system./
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文献和实验该产品被引用文献
Life science alliance 6: | PubMed 36878637
2023
Endemic Burkitt lymphoma avatar mouse models for exploring inter-patient tumor variation and testing targeted therapies.
out
Applications
Unspecified application
Species
Unspecified reactive species
Priya Saikumar Lakshmi, Cliff I Oduor, Catherine S Forconi, Viriato M'Bana, Courtney Bly, Rachel M Gerstein, Juliana A Otieno, John M Ong'echa, Christian Münz, Micah A Luftig, Michael A Brehm, Jeffrey A Bailey, Ann M Moormann
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文献支持
ab16126-250ug,Anti-EBNA 3A antibody
¥3215




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