ab13219-100ug，Anti-CD11+CD18 a

CD11+CD18 also known as integrin αLβ2 or LFA-1 is a heterodimeric protein complex with a molecular weight of approximately 180 kDa. It consists of two subunits CD11a (αL) and CD18 (β2) which are expressed on the surface of leukocytes such as neutrophils monocytes and lymphocytes. This complex plays an important role in cell-cell adhesion and interactions with the extracellular matrix. CD11+CD18 is an essential mediator of leukocyte adhesion and is involved in the immune response./ Biological function summary/ CD11a/CD18 enables leukocyte adhesion to endothelial cells and guides their migration towards sites of inflammation. It functions as part of a larger integrin family responsible for various cellular processes. The protein complex binds to its ligand ICAM-1 (Intercellular Adhesion Molecule 1) initiating a cascade of signaling events that facilitate immune surveillance and cell junction formation. This adhesion complex is integral to the regulation of immune system functions./