ab19962-500ul，Anti-Neisseria g

Neisseria gonorrhoeae also known as gonococcus is a Gram-negative bacterium that mechanically plays an integral role in facilitating infections particularly in mucous membranes. This pathogen has a mass of approximately 1.0 giga daltons. Gonococcus is expressed in the extracellular regions of human host tissues primarily in the urogenital tract. It uses specialized pili to adhere to epithelial cells helping it colonize and invade host tissues making it an efficient pathogen for transmission and infection./ Biological function summary/ Neisseria gonorrhoeae employs its numerous surface proteins to engage the host's defense mechanisms. One such important component is its ability to form a type IV pilus complex which assists in DNA uptake and nuancing of surface morphology. This bacterium also constitutes proteins like PorB a porin protein essential for nutrient uptake and immune evasion. By altering its surface structures through antigenic variation it adapts effectively to host immune responses. Gonococcal antibodies target these surface antigens to neutralize infection highlighting its complex interactions within the host./ Pathways/ Neisseria gonorrhoeae shares essential roles in modulating signaling mechanisms within immune response pathways. The bacterium influences the complement pathway rendering it a critical focus for immune modulation to avoid opsonization. Another vital pathway includes the activation of the bacterial type III secretion system facilitating translocation of effector proteins into host cells. Proteins like Opa encountered frequently in these pathways interact closely with host cell receptors modulating host-cell communication to enhance bacterial survival./