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- 详细信息
- 询价记录
- 文献和实验
- 技术资料
- 抗体名:
Anti-Nucleophosmin antibody [FC82291]
- 应用范围:
仅用科研
- 保质期:
见瓶身
- 库存:
99
- 供应商:
嘉兴亦高
- 保存条件:
-20°
- 规格:
50ul
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文献和实验作为免疫反应调节的细胞而发挥作用,但这些细胞的Fc受体的作用尚不甚明了。在人体,具有对IgM的Fc受体的细胞,是B细胞的助细胞,以及具有对IgG的受体细胞,是作为抑制细胞而起作用。(4)对肥大细胞的Fc受体结合的IgE,其进一步与抗原结合时,肥大细胞可释放出引起“即发型”过敏症因子。(5)非淋巴细胞性的某种细胞(K细胞),可与癌细胞同异种细胞结合的IgG的Fc部分结合,给这些细胞以障碍,这种现象称为抗体依赖性细胞障碍作用(antibody dependent cellular cytotoxi
Determination of Fc-Mediated Antibody-Effector Functions by Chromium Release Assay
Monoclonal antibodies (mAbs) can exert their biological functions by a large variety of mechanisms and have therefore become a major part in the treatment of diseases like viral infections and cancer. For the clinical efficacy of many mAbs Fc
to reduce immunogenicity, progress in antibody engineering now enables the generation of antibodies with novel interesting features. The introduction of Fc engineering technologies offers the potential to tailor Fc-mediated effector functions
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