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SAPS1 Rabbit pAb(bs-19388R)-50

ul/100ul/200ul
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  • ¥1180 - 2800
  • Bioss已认证
  • bs-19388R
  • 2025年10月25日
  • 产品信息以Bioss网站为准
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      50ul/100ul/200ul

    规格:50ul产品价格:¥1180.0
    规格:100ul产品价格:¥1980.0
    规格:200ul产品价格:¥2800.0
    产品编号bs-19388R
    英文名称SAPS1 Rabbit pAb
    中文名称SAPS结构域家族1抗体
    英文别名PP6R1; Protein phosphatase 6, regulatory subunit 1; SAP190; SAPS domain family, member 1.
    产品应用WB=1:500-2000

    Not yet tested in other applications.
    Optimal working dilutions must be determined by the end user.

    交叉反应Human, Mouse, Rat (Dog, Pig, Cow, Horse, Rabbit, Rhesus monkey, Gorilla, Orangutan)
    抗体来源Rabbit
    免疫原KLH conjugated synthetic peptide derived from human SAPS1
    亚型IgG
    性状Liquid
    纯化方法affinity purified by Protein A
    克隆类型Polyclonal
    理论分子量97 kDa
    浓度1mg/ml
    储存液0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
    亚基Protein phosphatase 6 (PP6) holoenzyme is proposed to be a heterotrimeric complex formed of the catalytic subunit, a SAPS domain-containing subunit (PP6R) and an ankyrin repeat-domain containing regulatory subunit (ARS). Interacts with PPP6C and NFKBIE. Interacts with ANKRD28, ANKRD44 and ANKRD52.
    亚细胞定位Cytoplasm
    组织特异性Ubiquitous with higher expression in testis.
    相似性Belongs to the SAPS family.
    功能Regulatory subunit of protein phosphatase 6 (PP6). May function as a scaffolding PP6 subunit. Involved in the PP6-mediated dephosphorylation of NFKBIE opposing its degradation in response to TNF-alpha.
    保存条件Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles.
    注意事项This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
    背景资料Protein phosphatase regulatory subunits, such as SAPS1, modulate the activity of protein phosphatase catalytic subunits by restricting substrate specificity, recruiting substrates, and determining the intracellular localization of the holoenzyme. SAPS1 is a regulatory subunit for the protein phosphatase-6 catalytic subunit (PPP6C; MIM 612725) (Stefansson and Brautigan, 2006 [PubMed 16769727]).[supplied by OMIM, Nov 2010]

     

    应用推荐稀释比例
    {WB}{1:500-2000}

     

    产品细节图片1
    Sample:
    Lane 1: Stomach (Mouse) Lysate at 40 ug
    Lane 2: Testis (Mouse) Lysate at 40 ug
    Lane 3: Lymph node (Mouse) Lysate at 40 ug
    Lane 4: Testis (Rat) Lysate at 40 ug
    Lane 5: HL60 (Human) Cell Lysate at 30 ug
    Lane 6: 293T (Human) Cell Lysate at 30 ug
    Lane 7: Molt-4 (Human) Cell Lysate at 30 ug
    Primary: Anti-SAPS1 (bs-19388R) at 1/1000 dilution
    Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution
    Predicted band size: 120 kD
    Observed band size: 120 kD

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    ¥1180 - 2800